Protein S/PROS1 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag

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Protein S/PROS1 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag: 产品信息

基因
种属
Human
NCBI 参考序列号
基因长度
2031 bp
序列特征
Identical with the Gene Bank Ref. ID sequence (Nucleotide may contain silent mutation without changing amino acid sequence)
产品特征
Full length Clone DNA of Homo sapiens protein S (alpha).
质粒
启动子
Enhanced CMV mammalian cell promoter
标签序列
GFPSpark Tag Sequence: GTGAGCAAGGGC……GAGCTGTACAAG
测序引物
pLen-F(CTCGTTTAGTGAACCGTCAGAATT), pLen-R(GAACCGGAACCCTTAAACATGT)
质控
The plasmid is confirmed by full-length sequencing.
筛选
细菌筛选抗性
Ampicillin
储存 & 运输
运输方式
Each tube contains 10μg lyophilized plasmid
储存条件
The lyophilized plasmid can be stored at room temperature for three months

Protein S/PROS1 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag: 别称

PROS cDNA ORF Clone, Human; Protein S cDNA ORF Clone, Human; PS21 cDNA ORF Clone, Human; PS22 cDNA ORF Clone, Human; PS23 cDNA ORF Clone, Human; PS24 cDNA ORF Clone, Human; PS25 cDNA ORF Clone, Human; PSA cDNA ORF Clone, Human; THPH5 cDNA ORF Clone, Human; THPH6 cDNA ORF Clone, Human

Protein S/PROS1 背景信息

PROS1, also known as protein S, is a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. PROS1 has two isoforms: a free, functionally active form and an inactive form complexed with C4b-binding protein. Besides its anticoagulant function, PROS1 also acts as an agonist for the tyrosine kinase receptors Tyro3, Axl, and Mer. The endothelium expresses Tyro3, Axl, and Mer and produces protein S. The interaction of protein S with endothelial cells and particularly its effects on angiogenesis have not yet been analyzed.
全称
protein S (alpha)
参考文献
  • Beauchamp NJ. et al., 2004, Br J Haematol. 125 (5): 647-54.
  • García de Frutos P. et al., 2007, Thromb Haemost. 98 (3): 543-56.
  • Rezende SM. et al., 2004, Blood. 103 (4): 1192-201.
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