RPA3 cDNA ORF Clone in Cloning Vector, Human
Cat: HG19155-U
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RPA3 cDNA ORF Clone in Cloning Vector, Human: 产品信息
基因
种属
Human
NCBI 参考序列号
基因长度
366 bp
序列特征
Identical with the Gene Bank Ref. ID sequence.
产品特征
Full length Clone DNA of Human replication protein A3
质粒
筛选
细菌筛选抗性
Ampicillin
储存 & 运输
运输方式
Each tube contains lyophilized plasmid.
储存条件
The lyophilized plasmid can be stored at ambient temperature for three months.
RPA3 cDNA ORF 核苷酸序列及氨基酸序列信息
**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**
关于 RPA3的更多信息
Entrez Gene ID
RPA3 cDNA ORF Clone in Cloning Vector, Human: 别称
REPA3 cDNA ORF Clone, Human; RP-A p14 cDNA ORF Clone, Human
RPA3 背景信息
The replication protein A3 (RPA3) gene is located on chromosome 7p22. RPA3 is a component of the RPA protein complex, which plays an essential role in multiple processes of DNA metabolism. RPA3 is upregulated in hepatocellular carcinoma (HCC) and gastric cancer tissues. High expression of RPA3 is associated with poorer patient survival. RPA3 represents a new therapeutic target of gastric cancer as well as hepatocellular carcinoma and serves as a potential prognostic biomarker for patient survival.
参考文献
- Qu C, et al. (2017) Rpa3 is a potential marker of prognosis and radioresistance for nasopharyngeal carcinoma. J Cell Mol Med 21 (11): 2872-2883.
- Jin T, et al. (2013) Tp53 and rpa3 gene variations were associated with risk of glioma in a chinese han population. Cancer Biother Radiopharm 28 (3): 248-253.
- Dai Z, et al. (2017) Elevated expression of rpa3 is involved in gastric cancer tumorigenesis and associated with poor patient survival. Dig Dis Sci 62 (9): 2369-2375.
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