SLC38A1 cDNA ORF Clone, Human, N-HA tag

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SLC38A1 cDNA ORF Clone, Human, N-HA tag: 产品信息

基因
种属
Human
NCBI 参考序列号
基因长度
1464 bp
产品特征
Full length Clone DNA of Human solute carrier family 38, member 1 with N terminal HA tag.
质粒
启动子
Enhanced CMV promoter
载体
标签序列
HA Tag Sequence: TATCCTTACGACGTGCCTGACTACGCC
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.
筛选
细菌筛选抗性
Kanamycin
细胞筛选抗性
Hygromycin
应用
Stable or Transient mammalian expression
储存 & 运输
运输方式
Each tube contains lyophilized plasmid.
储存条件
The lyophilized plasmid can be stored at ambient temperature for three months.

关于 SLC38A1的更多信息

Entrez Gene ID

SLC38A1 cDNA ORF Clone, Human, N-HA tag: 别称

ATA1 cDNA ORF Clone, Human; NAT2 cDNA ORF Clone, Human; SAT1 cDNA ORF Clone, Human; SNAT1 cDNA ORF Clone, Human

SLC38A1 背景信息

SLC38A1 (Solute Carrier Family 38 Member 1) is a Protein Coding gene. The SLC38A1 gene, located on 12q13.11, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, and frog. SLC38A1 is an important transporter of glutamine, an intermediate in the detoxification of ammonia and the production of urea. Glutamine serves as a precursor for the synaptic transmitter, glutamate. SLC38A1 is widely expressed in the lymph node, thyroid, and other tissues. Diseases associated with SLC38A1 include Klatskin's Tumor. SLC38A1 is associated with the occurrence and progression of solid tumors. Further, glutamine transporter SLC38A1 might serve as a potential target for the development of novel therapeutic drugs in the treatment of acute myeloid leukemia (AML).
全称
solute carrier family 38, member 1
参考文献
  • Qureshi T, et al. (2020) Slc38a1 conveys astroglia-derived glutamine into gabaergic interneurons for neurotransmitter gaba synthesis. Cells 9 (7): 1686.
  • Qureshi T, et al. (2019) The glutamine transporter slc38a1 regulates gabaergic neurotransmission and synaptic plasticity. Cereb Cortex 29 (12): 5166-5179.
  • Li Y, et al. (2019) High expression of slc38a1 predicts poor prognosis in patients with de novo acute myeloid leukemia. J Cell Physiol 234 (11): 20322-20328.
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