Sphingosine Kinase 1 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag

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Sphingosine Kinase 1 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag: 产品信息

基因
种属
Human
NCBI 参考序列号
基因长度
1155 bp
序列特征
Identical with the Gene Bank Ref. ID sequence (Nucleotide may contain silent mutation without changing amino acid sequence)
产品特征
Full length Clone DNA of Homo sapiens sphingosine kinase 1.
质粒
启动子
Enhanced CMV mammalian cell promoter
标签序列
GFPSpark Tag Sequence: GTGAGCAAGGGC……GAGCTGTACAAG
测序引物
pLen-F(CTCGTTTAGTGAACCGTCAGAATT), pLen-R(GAACCGGAACCCTTAAACATGT)
质控
The plasmid is confirmed by full-length sequencing.
筛选
细菌筛选抗性
Ampicillin
储存 & 运输
运输方式
Each tube contains 10μg lyophilized plasmid
储存条件
The lyophilized plasmid can be stored at room temperature for three months

Sphingosine Kinase 1 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag: 别称

SPHK cDNA ORF Clone, Human; SPHK1 cDNA ORF Clone, Human; SPK cDNA ORF Clone, Human

Sphingosine Kinase 1 背景信息

SPHK1, also known as sphingosine Kinase 1, catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P). S1P exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. It is a ligand for cell surface G protein-coupled receptors. SPHK 1 is a potential therapeutic target for the control of cancer and inflammation. SPHK1 plays a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes.
全称
sphingosine kinase 1
参考文献
  • Kohama T. et al., 1998, J Biol Chem. 273 (37): 23722-8.
  • Xia P. et al., 2002, J Biol Chem. 277 (10): 7996-8003.
  • Tsukahara T. et al., 2002, Tanpakushitsu Kakusan Koso. 47 (4): 509-13.
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