ATF1 cDNA ORF Clone, Mouse, N-GFPSpark® tag

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ATF1 cDNA ORF Clone, Mouse, N-GFPSpark® tag: 产品信息

基因
种属
Mouse
NCBI 参考序列号
基因长度
810 bp
产品特征
Full length Clone DNA of Mouse activating transcription factor 1 with N terminal GFPSpark tag.
质粒
启动子
Enhanced CMV promoter
标签序列
GFPSpark: GTGAGCAAGGGC……GAGCTGTACAAG
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.
筛选
细菌筛选抗性
Kanamycin
细胞筛选抗性
Hygromycin
应用
Stable or Transient mammalian expression
储存 & 运输
运输方式
Each tube contains lyophilized plasmid.
储存条件
The lyophilized plasmid can be stored at ambient temperature for three months.

关于 ATF1的更多信息

Entrez Gene ID

ATF1 背景信息

Activating transcription factor 1 (ATF1) and RAS genes were significantly up-regulated in tumours of both primary and recurrent cervical cancer mouse model, and they can also be detected in the blood exosomes of the mouse model. Our results indicated that ATF1 and RAS could be potential candidate biomarkers for cervical cancer in early diagnosis. ATF1 and RAS genes were found significantly elevated in tumours of primary and recurrent cervical cancer mouse model, and they were also detected in the blood exosomes. Therefore, ATF1 and RAS could be used as a diagnostic marker for cervical cancer in the future. The transcription factor Atf1 is known to promote cell survival during various stress conditions in Schizosaccharomyces pombe by activating the expression of appropriate genes. It can also activate transcription of other important genes responsible for cell cycle progression. An Atf1-dependent increase in the expression of cell division promoting genes will oppose activation of checkpoints necessary to ensure repairs and cell survival during stress.
全称
activating transcription factor 1
Related Pathways
  • MAPK-Erk Pathway
    MAPK-Erk Pathway
  • P38 MAPK Signaling Pathway
    P38 MAPK Signaling Pathway
  • IL1 signaling pathway
    IL1 signaling pathway
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