HDAC1 cDNA ORF Clone, Mouse, C-GFPSpark® tag

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HDAC1 cDNA ORF Clone, Mouse, C-GFPSpark® tag: 产品信息

基因
种属
Mouse
NCBI 参考序列号
基因长度
1449 bp
产品特征
Full length Clone DNA of Mouse histone deacetylase 1 with C terminal GFPSpark tag.
质粒
启动子
Enhanced CMV promoter
标签序列
GFPSpark: GTGAGCAAGGGC……GAGCTGTACAAG
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.
筛选
细菌筛选抗性
Kanamycin
细胞筛选抗性
Hygromycin
应用
Stable or Transient mammalian expression
储存 & 运输
运输方式
Each tube contains lyophilized plasmid.
储存条件
The lyophilized plasmid can be stored at ambient temperature for three months.

HDAC1 cDNA ORF Clone, Mouse, C-GFPSpark® tag: 别称

HD1 cDNA ORF Clone, Mouse; Hdac1-ps cDNA ORF Clone, Mouse; MommeD5 cDNA ORF Clone, Mouse; RPD3 cDNA ORF Clone, Mouse

HDAC1 背景信息

HDAC1 (Histone Deacetylase 1) is a Protein Coding gene. Histone Deacetylase 1 protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. HDAC1 is a ubiquitous deacetylase enzyme responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3, and H4). Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. HDAC1 is widely expressed in the lymph node, colon, and other tissues. Diseases associated with HDAC1 include Atrichia With Papular Lesions and Retinoblastoma.
全称
histone deacetylase 1
研究领域
Related Pathways
  • Notch Signaling
    Notch Signaling
  • p53 Pathway
    p53 Pathway
参考文献
  • Beharry AW, Sandesara PB, Roberts BM, Ferreira LF, Senf SM, Judge AR. HDAC1 activates FoxO and is both sufficient and required for skeletal muscle atrophy. Journal of Cell Science. 2014;127(7):1441-1453.
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