HDAC1 cDNA ORF Clone, Mouse, N-OFPSpark® tag

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HDAC1 cDNA ORF Clone, Mouse, N-OFPSpark® tag: 产品信息

基因
种属
Mouse
NCBI 参考序列号
基因长度
1449 bp
产品特征
Full length Clone DNA of Mouse histone deacetylase 1 with N terminal OFPSpark / RFP tag.
质粒
启动子
Enhanced CMV promoter
标签序列
OFPSpark Tag: GATAGCACTGAG……CACCTGTTCCAG
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.
筛选
细菌筛选抗性
Kanamycin
细胞筛选抗性
Hygromycin
应用
Stable or Transient mammalian expression
储存 & 运输
运输方式
Each tube contains lyophilized plasmid.
储存条件
The lyophilized plasmid can be stored at ambient temperature for three months.

Citation List

HDAC1 cDNA ORF Clone, Mouse, N-OFPSpark® tag: 别称

HD1 cDNA ORF Clone, Mouse; Hdac1-ps cDNA ORF Clone, Mouse; MommeD5 cDNA ORF Clone, Mouse; RPD3 cDNA ORF Clone, Mouse

HDAC1 背景信息

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. Histone Deacetylase 1 protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
全称
histone deacetylase 1
研究领域
Related Pathways
  • Notch Signaling
    Notch Signaling
  • p53 Pathway
    p53 Pathway
参考文献
  • Beharry AW, Sandesara PB, Roberts BM, Ferreira LF, Senf SM, Judge AR. HDAC1 activates FoxO and is both sufficient and required for skeletal muscle atrophy. Journal of Cell Science. 2014;127(7):1441-1453.
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