HDAC1 cDNA ORF Clone, Mouse, N-Myc tag

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HDAC1 cDNA ORF Clone, Mouse, N-Myc tag: 产品信息

基因
种属
Mouse
NCBI 参考序列号
基因长度
1494 bp
序列特征
Identical with the Gene Bank Ref. ID sequence except for the point mutations: 633G/A not causing the amino acid variation.
产品特征
Full length Clone DNA of Mouse histone deacetylase 1 with N terminal Myc tag.
质粒
启动子
Enhanced CMV promoter
载体
限制性酶切位点
KpnI + XbaI(6kb+1.49kb)
标签序列
Myc Tag Sequence: GAGCAGAAACTCATCTCAGAAGAGGATCTG
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.
筛选
细菌筛选抗性
Kanamycin
细胞筛选抗性
Hygromycin
应用
Stable or Transient mammalian expression
储存 & 运输
运输方式
Each tube contains lyophilized plasmid.
储存条件
The lyophilized plasmid can be stored at ambient temperature for three months.

HDAC1 cDNA ORF 核苷酸序列及氨基酸序列信息

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

HDAC1 cDNA ORF Clone, Mouse, N-Myc tag: 验证图片

Citation List

HDAC1 cDNA ORF Clone, Mouse, N-Myc tag: 别称

HD1 cDNA ORF Clone, Mouse; Hdac1-ps cDNA ORF Clone, Mouse; MommeD5 cDNA ORF Clone, Mouse; RPD3 cDNA ORF Clone, Mouse

HDAC1 背景信息

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. Histone Deacetylase 1 protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
全称
histone deacetylase 1
研究领域
Related Pathways
  • Notch Signaling
    Notch Signaling
  • p53 Pathway
    p53 Pathway
参考文献
  • Beharry AW, Sandesara PB, Roberts BM, Ferreira LF, Senf SM, Judge AR. HDAC1 activates FoxO and is both sufficient and required for skeletal muscle atrophy. Journal of Cell Science. 2014;127(7):1441-1453.
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