Serglycin cDNA ORF Clone, Mouse, N-HA tag

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Serglycin cDNA ORF Clone, Mouse, N-HA tag: 产品信息

基因
种属
Mouse
NCBI 参考序列号
基因长度
459 bp
产品特征
Full length Clone DNA of Mouse serglycin with N terminal HA tag.
质粒
启动子
Enhanced CMV promoter
载体
标签序列
HA Tag Sequence: TATCCTTACGACGTGCCTGACTACGCC
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.
筛选
细菌筛选抗性
Kanamycin
细胞筛选抗性
Hygromycin
应用
Stable or Transient mammalian expression
储存 & 运输
运输方式
Each tube contains lyophilized plasmid.
储存条件
The lyophilized plasmid can be stored at ambient temperature for three months.

Citation List

Serglycin cDNA ORF Clone, Mouse, N-HA tag: 别称

Prg cDNA ORF Clone, Mouse; Prg1 cDNA ORF Clone, Mouse; Sgc cDNA ORF Clone, Mouse

Serglycin 背景信息

SRGN is known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of various hematopoietic cells has a protease-resistant peptide core, and is vital for neutralizing hydrolytic enzymes. SRGN is associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. It is required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. SRGN also plays a role in localizing neutrophil elastase in azurophil granules of neutrophils.
全称
serglycin
参考文献
  • Hatton MN. et al., 1985, Biochem J. 230 (3): 817-20.
  • Schick BP. et al., 1995, J Cell Physiol. 165 (1): 96-106.
  • Kato S. et al., 1995, Gene. 150 (2): 243-50.
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