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人 S100A1 基因ORF全长cDNA克隆(表达载体), C-Flag 标签

产品数据评论实验方法
描述: Active  
表达宿主: Human Cells  
  • Slide 1
10179-H01H-50
10179-H01H-100
50 µg 
100 µg 
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描述: Active  
表达宿主: E. coli  
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10179-HNAE-50
10179-HNAE-100
50 µg 
100 µg 
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描述: Active  
表达宿主: E. coli  
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50266-M07E-50
50266-M07E-100
50 µg 
100 µg 
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反应性: Mouse  
应用 : ELISA  
    50266-R148-50
    50266-R148-100
    50266-R148-1
    50 µg 
    100 µg 
    1 mg 
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    反应性: Mouse  
    应用 : IHC-P  
    • Slide 1
    • Slide 1
    50266-R004-50
    50266-R004-100
    50 µg 
    100 µg 
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    反应性: Mouse  
    应用 : 
      50266-R049-50
      50266-R049-100
      50266-R049-1
      50 µg 
      100 µg 
      1 mg 
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      反应性: Mouse  
      应用 : ELISA  WB  IHC-P  
      • Slide 1
      • Slide 1
      • Slide 1
      • Slide 1
      50266-RP02-50
      50266-RP02-200
      50266-RP02-100
      50 µg 
      200 µg 
      100 µg 
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      反应性: Mouse  
      应用 : ELISA  
        50266-RP01-400
        50266-RP01-200
        50266-RP01-100
        400 µg 
        200 µg 
        100 µg 
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        反应性: Mouse  
        应用 : IHC-P  
        • Slide 1
        50266-R242-50
        50266-R242-100
        50 µg 
        100 µg 
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        S100A1 ELISA配对抗体

        检测限:
        SEK50266-5
        SEK50266-15
        5 Plates 
        15 Plates 
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        S100A1 cDNARelated Products

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        S100A1 cdna-clone 研究背景

        S100A1 is a Ca2+binding protein of the EF-hand type that belongs to the S100 protein family. S100 proteins consisting of at least 19 members exist as dimers in the cytoplasm and/or nucleus of a wide range of cells, and are involved in the regulation of a number of cellular processes such as cell-cycle progression and cell differentiation.This protein has been shown to function in the processes including stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of PKC-mediated phosphorylation.. Phosphoglucomutase is a target protein whose activity is antagonistically regulated by S100A1, and recently, S100A1 is also identified as a potent molecular chaperone and a new member of the Hsp70/Hsp90 multichaperone complex. S100A1 displays a tissue-specific expression pattern with highest levels in myocardium and is considered to be an important regulator of cardiac contractility. Accordingly, reduced expression or mutations of S100A1 gene have been implicated in cardiomyopathies.

         S100A1 cdna-clone 参考资料
      • Remppis, A .et al., 1996, Biochim. Biophs. Acta. 1313: 253-257.
      • Most, P. et al., 2001, Proc. Natl. Acad. Sci. U.S.A. 98: 13889-13894
      • Okada, M. et al., 2004, J. Biol. Chem. 279: 4221-4233.
      • Schafer, W.E. et al., 1995, Genomics. 25: 638-643.
      • Landar, A. et al., 1996, Cell. Calcium. 20: 279-285.
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