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人 VEGFR1 / FLT-1 蛋白 (His 标签)

产品数据评论实验方法
反应性: Human  
应用 : FCM  
  • Slide 1
10136-R111-F-25
10136-R111-F-100
25 Test 
100 Tests 
Add to Cart
反应性: Human  
应用 : FCM  
  • Slide 1
10136-R111-P-25
10136-R111-P-100
25 Test 
100 Tests 
Add to Cart
反应性: Human  
应用 : ELISA  
    10136-MM03-50
    10136-MM03-200
    10136-MM03-100
    50 µg 
    200 µg 
    100 µg 
    Add to Cart
    反应性: Human  
    应用 : FCM  
    • Slide 1
    10136-R111-50
    10136-R111-100
    50 µg 
    100 µg 
    Add to Cart
    反应性: Human  
    应用 : ELISA  
      10136-RP01-400
      10136-RP01-200
      10136-RP01-100
      400 µg 
      200 µg 
      100 µg 
      Add to Cart
      反应性: Human  
      应用 : ELISA  
        10136-RP02-50
        10136-RP02-200
        10136-RP02-100
        50 µg 
        200 µg 
        100 µg 
        Add to Cart
        反应性: Rat  
        应用 : ELISA  
          80101-T16-50
          80101-T16-200
          80101-T16-100
          50 µg 
          200 µg 
          100 µg 
          Add to Cart
          反应性: Rat  
          应用 : ELISA  
            80101-RP01-400
            80101-RP01-200
            80101-RP01-100
            400 µg 
            200 µg 
            100 µg 
            Add to Cart
            反应性: Rat  
            应用 : 
              80101-R034-50
              80101-R034-100
              50 µg 
              100 µg 
              Add to Cart

              HP100207 

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              VEGFR1/FLT-1 protein 研究背景

              Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a single-pass type I membrane protein and secreted protein which belongs to the protein kinase superfamily, Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 / FLT1 contains seven Ig-like C2-type (immunoglobulin-like) domains and one protein kinase domain. VEGFR-1 / FLT1 is expressed mostly in normal lung, but also in placenta, liver, kidney, heart and brain tissues. It is specifically expressed in most of the vascular endothelial cells, and also expressed in peripheral blood monocytes. VEGFR-1 / FLT1 is not expressed in tumor cell lines. VEGFR-1 / FLT1 is an essential receptor tyrosine kinase that regulates mammalian vascular development and embryogenesis. EGF-induced angiogenesis requires inverse regulation of VEGFR-1 and VEGFR-2 in tumor-associated endothelial cells. VEGFR-1 / FLT1 is a receptor for VEGF, VEGFB and PGF. It has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.

              Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

               VEGFR1/FLT-1 protein 参考资料
              请注意:所有产品都是“仅用于科研,而不能用于诊断或治疗用途”