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大鼠 P-Selectin/CD62P/SELP 基因ORF全长cDNA克隆(表达载体)

产品数据评论实验方法
表达宿主: Human Cells  
  • Slide 1
13025-H02H-50
13025-H02H-100
50 µg 
100 µg 
Add to Cart
表达宿主: Human Cells  
  • Slide 1
13025-H08H-50
13025-H08H-100
50 µg 
100 µg 
Add to Cart
表达宿主: Human Cells  
  • Slide 1
50737-M02H-50
50737-M02H-100
50 µg 
100 µg 
Add to Cart
表达宿主: Human Cells  
  • Slide 1
50737-M08H-50
50737-M08H-100
50 µg 
100 µg 
Add to Cart
表达宿主: Human Cells  
  • Slide 1
80451-R02H-50
80451-R02H-100
50 µg 
100 µg 
Add to Cart
表达宿主: Human Cells  
  • Slide 1
80451-R08H-50
80451-R08H-100
50 µg 
100 µg 
Add to Cart
表达宿主: Human Cells  
  • Slide 1
90170-C02H-50
90170-C02H-200
50 µg 
200 µg 
Add to Cart
表达宿主: Human Cells  
  • Slide 1
90170-C08H-50
90170-C08H-100
50 µg 
100 µg 
Add to Cart
反应性: Human  
应用 : ELISA  
    13025-R001-50
    13025-R001-100
    50 µg 
    100 µg 
    Add to Cart
    反应性: Human  
    应用 : ELISA  
      13025-MM03-50
      13025-MM03-200
      13025-MM03-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      反应性: Human  
      应用 : ELISA  
        13025-RP01-400
        13025-RP01-200
        13025-RP01-100
        400 µg 
        200 µg 
        100 µg 
        Add to Cart
        反应性: Human  
        应用 : ELISA  
          13025-T16-50
          13025-T16-200
          13025-T16-100
          50 µg 
          200 µg 
          100 µg 
          Add to Cart
          反应性: Mouse  
          应用 : 
            50737-R001-50
            50737-R001-100
            50 µg 
            100 µg 
            Add to Cart
            反应性: Mouse  
            应用 : ELISA  
              50737-RP01-400
              50737-RP01-200
              50737-RP01-100
              400 µg 
              200 µg 
              100 µg 
              Add to Cart
              反应性: Mouse  
              应用 : ELISA  
                50737-T16-50
                50737-T16-200
                50737-T16-100
                50 µg 
                200 µg 
                100 µg 
                Add to Cart
                反应性: Rhesus  
                应用 : ELISA  
                  90170-RP01-400
                  90170-RP01-200
                  90170-RP01-100
                  400 µg 
                  200 µg 
                  100 µg 
                  Add to Cart
                  反应性: Rhesus  
                  应用 : ELISA  WB  
                  • Slide 1
                  90170-T48-50
                  90170-T48-200
                  90170-T48-100
                  50 µg 
                  200 µg 
                  100 µg 
                  Add to Cart

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                  P-Selectin/CD62P/SELP cdna-clone 研究背景

                  P selectin (SELP) is a 140kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. SELP mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1. P selectin is a cell adhesion molecule on the surface of activated endothelial cells. Cellular adhesion molecules are a large family of proteins that attach the cytoskeleton and intracellular signaling cascades with the extracellular environment. SELP is a calcium-dependent receptor for myeloid cells that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interacton of activated endothelial cells or platelets with leukocytes.

                  大鼠 P-Selectin/CD62P/SELP cdna-clone 参考资料
                • Johnson-Tidey RR, et al. (1994) Increase in the adhesion molecule P-selectin in endothelium overlying atherosclerotic plaques. Coexpression with intercellular adhesion molecule-1. Am J Pathol. 144(5):952-61.
                • Walcheck B, et al. (1996) Neutrophil-neutrophil interactions under hydrodynamic shear stress involve L-selectin and PSGL-1. A mechanism that amplifies initial leukocyte accumulation of P-selectin in vitro. J Clin Invest. 98(5):1081-7.
                • Foreman KE, et al. (1994) C5a-induced expression of P-selectin in endothelial cells. J Clin Invest. 94(3):1147-55.
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