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大鼠 IL-5/IL5 / Interleukin 5 基因ORF全长cDNA克隆(表达载体)

产品数据评论实验方法
描述:   
表达宿主: E. coli  
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15673-HNCE-5
15673-HNCE-20
15673-HNCE-100
5 µg 
20 µg 
100 µg 
Add to Cart
描述: Active  
表达宿主: Baculovirus-Insect Cells  
  • Slide 1
51068-M08B-5
51068-M08B-20
51068-M08B-100
5 µg 
20 µg 
100 µg 
Add to Cart
表达宿主: Baculovirus-Insect Cells  
  • Slide 1
70019-D08B-5
70019-D08B-20
70019-D08B-100
5 µg 
20 µg 
100 µg 
Add to Cart
反应性: Human  
应用 : ELISA  
    15673-MM02-50
    15673-MM02-200
    15673-MM02-100
    50 µg 
    200 µg 
    100 µg 
    Add to Cart
    反应性: Human  
    应用 : 
      15673-MM13-50
      15673-MM13-200
      15673-MM13-100
      15673-MM13-1
      50 µg 
      200 µg 
      100 µg 
      1 mg 
      Add to Cart
      反应性: Human  
      应用 : ELISA  WB  
      • Slide 1
      15673-T48-50
      15673-T48-200
      15673-T48-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      反应性: Human  
      应用 : 
      • Slide 1
      15673-R013-500
      15673-R013-200
      500 µg 
      200 µg 
      Add to Cart
      反应性: Mouse  
      应用 : ELISA  
        51068-T16-50
        51068-T16-200
        51068-T16-100
        50 µg 
        200 µg 
        100 µg 
        Add to Cart
        反应性: Mouse  
        应用 : ELISA  WB  
        • Slide 1
        51068-T48-50
        51068-T48-200
        51068-T48-100
        50 µg 
        200 µg 
        100 µg 
        Add to Cart
        反应性: Mouse  
        应用 : ELISA  
          51068-RP01-400
          51068-RP01-200
          51068-RP01-100
          400 µg 
          200 µg 
          100 µg 
          Add to Cart
          反应性: Mouse  
          应用 : 
            51068-R121-50
            51068-R121-100
            50 µg 
            100 µg 
            Add to Cart
            反应性: Canine  
            应用 : ELISA  
              70019-RP01-400
              70019-RP01-200
              70019-RP01-100
              400 µg 
              200 µg 
              100 µg 
              Add to Cart

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              IL-5/IL5 / Interleukin 5 cdna-clone 研究背景

              Interleukin 5 (IL-5) is a member of the interleukin family with length of 115 amino acids. Interleukins are a group of cytokines (secreted proteins / signaling molecules) that were first seen to be expressed by white blood cells (leukocytes) and has been found in a wide variety of body cells. Interleukin 5 or IL-5 is produced by T helper-2 cells and mast cells. It helps to stimulate B cell growth and increase immunoglobulin secretion and is considered as a key mediator in eosinophil activation. Interleukin 5 (IL-5) has long been associated with several allergic diseases, including allergic rhinitis and asthma. Growth in the number of circulating, airway tissue, and induced sputum eosinophils have been observed in patients with these diseases. IL-5 also had something with the terminally differentiated granulocyte eosinophils. IL-5 was originally found as an eosinophil colony stimulating factor. It has been proved to be a major regulator of eosinophil accumulation in tissues, and can modulate eosinophil behavior at every stage from maturation to survival.

              大鼠 IL-5/IL5 / Interleukin 5 cdna-clone 参考资料
            • Milburn MV, et al. (1993) A novel dimer configuration revealed by the crystal structure at 2.4 A resolution of human interleukin-5. Nature. 363(6425): 172-176.
            • Lee JS, et al. (1989) The IL-4 and IL-5 genes are closely linked and are part of a cytokine gene cluster on mouse chromosome 11. Somat Cell Mol Genet. 15(2): 143-152.
            • Woodcock JM, et al. (1994) Three residues in the common beta chain of the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity binding and interact with Glu21 of GM-CSF. EMBO J. 13 (21): 5176-85.
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