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人 CD30/TNFRSF8 基因ORF全长cDNA克隆(表达载体), N-Flag 标签

产品数据评论实验方法
描述: Active  
表达宿主: Human Cells  
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10777-H03H-200
10777-H03H-100
200 µg 
100 µg 
Add to Cart
描述: Active  
表达宿主: Human Cells  
  • Slide 1
10777-H08H-200
10777-H08H-100
200 µg 
100 µg 
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反应性: Human  
应用 : FCM  
  • Slide 1
10777-R002-A-25
10777-R002-A-100
25 Test 
100 Tests 
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反应性: Human  
应用 : FCM  
  • Slide 1
10777-R002-P-25
10777-R002-P-100
25 Test 
100 Tests 
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反应性: Human  
应用 : FCM  
  • Slide 1
  • Slide 1
10777-MM05-P-25
10777-MM05-P-100
25 Test 
100 Tests 
Add to Cart
反应性: Human  
应用 : FCM  
  • Slide 1
  • Slide 1
10777-MM05-F-25
10777-MM05-F-100
25 Test 
100 Tests 
Add to Cart
反应性: Human  
应用 : FCM  
  • Slide 1
10777-MM05-A-25
10777-MM05-A-100
25 Test 
100 Tests 
Add to Cart
反应性: Human  
应用 : ELISA  
    10777-RP01-400
    10777-RP01-200
    10777-RP01-100
    400 µg 
    200 µg 
    100 µg 
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    反应性: Human  
    应用 : ELISA  
      10777-MM06-50
      10777-MM06-200
      10777-MM06-100
      50 µg 
      200 µg 
      100 µg 
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      反应性: Human  
      应用 : 
        10777-MM08-50
        10777-MM08-200
        10777-MM08-100
        10777-MM08-1
        50 µg 
        200 µg 
        100 µg 
        1 mg 
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        反应性: Human  
        应用 : ELISA  WB  IHC-P  IP  
        • Slide 1
        • Slide 1
        • Slide 1
        10777-RP02-50
        10777-RP02-200
        10777-RP02-100
        50 µg 
        200 µg 
        100 µg 
        Add to Cart
        反应性: Human  
        应用 : FCM  
        • Slide 1
        10777-MM05-50
        10777-MM05-200
        10777-MM05-100
        50 µg 
        200 µg 
        100 µg 
        Add to Cart
        反应性: Human  
        应用 : ELISA  
          10777-R015-50
          10777-R015-100
          10777-R015-1
          50 µg 
          100 µg 
          1 mg 
          Add to Cart
          反应性: Human  
          应用 : ELISA  
            10777-MM01-50
            10777-MM01-200
            10777-MM01-100
            50 µg 
            200 µg 
            100 µg 
            Add to Cart
            反应性: Mouse  
            应用 : IHC-P  
            • Slide 1
            101923-T08-50
            101923-T08-200
            101923-T08-100
            50 µg 
            200 µg 
            100 µg 
            Add to Cart

            CD30/TNFRSF8 cDNARelated Products

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            CD30/TNFRSF8 cdna-clone 研究背景

            CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of lymphocytes and may also play an important role in human immunodeficiency virus replication. As a regulator of apoptosis, CD30 protein induces cell death or proliferation, depending on the cell type, and has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. CD30 protein expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin's disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin's lymphomas (NHLs), and CD30 is also linked to leukocytes in patients with chronic inflammatory diseases, including lupus erythematosus, asthma, rheumatoid arthritis and atopic dermatitis (AD).

            Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

             CD30/TNFRSF8 cdna-clone 参考资料
          • Rossi FM, et al. (2001) CD30L up-regulates CD30 and IL-4 expression by T cells. FEBS Lett. 508(3): 418-22.
          • Trovato M, et al. (2001) Expression of CD30 ligand and CD30 receptor in normal thyroid and benign and malignant thyroid nodules. Thyroid. 11(7): 621-8.
          • Ekstrom ES, et al. (2001) Presence of CD30(+) and CD30L(+) cells in human placenta and soluble CD30 levels in cord blood are independent of maternal atopy. Placenta. 22(4): 372-9.
          • Tang C, et al. (2008) A novel role of CD30L/CD30 signaling by T-T cell interaction in Th1 response against mycobacterial infection. J Immunol. 181(9): 6316-27.
          • Sun X, et al. (2008) A critical role of CD30 ligand/CD30 in controlling inflammatory bowel diseases in mice. Gastroenterology. 134(2): 447-58.
          • Oflazoglu E, et al. (2009) Targeting CD30/CD30L in Oncology and Autoimmune and Inflammatory Diseases.Adv Exp Med Biol. 647: 174-85.
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