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大鼠 IL13/IL-13/ALRH 基因ORF全长cDNA克隆(表达载体)

产品数据评论实验方法
描述: Active  
表达宿主: Human Cells  
  • Slide 1
10369-H01H-20
10369-H01H-10
20 µg 
10 µg 
Add to Cart
描述: Active  
表达宿主: CHO Stable Cells  
  • Slide 1
10369-HNAC-500
10369-HNAC-5
10369-HNAC-20
10369-HNAC-100
10369-HNAC-1
500 µg 
5 µg 
20 µg 
100 µg 
1 mg 
Add to Cart
描述:   
表达宿主: Human Cells  
  • Slide 1
50225-MNAH-20
50225-MNAH-100
20 µg 
100 µg 
Add to Cart
描述: Active  
表达宿主: Human Cells  
  • Slide 1
11057-CNAH-500
11057-CNAH-5
11057-CNAH-20
11057-CNAH-100
11057-CNAH-1
500 µg 
5 µg 
20 µg 
100 µg 
1 mg 
Add to Cart
描述: Active  
表达宿主: Human Cells  
  • Slide 1
11057-C07H-5
11057-C07H-20
11057-C07H-100
5 µg 
20 µg 
100 µg 
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反应性: Human  
应用 : ELISA  
    10369-MM01-50
    10369-MM01-200
    10369-MM01-100
    50 µg 
    200 µg 
    100 µg 
    Add to Cart
    反应性: Human  
    应用 : 
      10369-MM15-50
      10369-MM15-200
      10369-MM15-100
      10369-MM15-1
      50 µg 
      200 µg 
      100 µg 
      1 mg 
      Add to Cart
      反应性: Human  
      应用 : 
        10369-MM02T-50
        10369-MM02T-200
        10369-MM02T-100
        10369-MM02T-1
        50 µg 
        200 µg 
        100 µg 
        1 mg 
        Add to Cart
        反应性: Human  
        应用 : ELISA  
          10369-RP02-50
          10369-RP02-200
          10369-RP02-100
          50 µg 
          200 µg 
          100 µg 
          Add to Cart
          反应性: Human  
          应用 : ELISA  
            10369-RP01-400
            10369-RP01-200
            10369-RP01-100
            400 µg 
            200 µg 
            100 µg 
            Add to Cart
            反应性: Human  
            应用 : ELISA  
              10369-R062-50
              10369-R062-100
              50 µg 
              100 µg 
              Add to Cart
              反应性: Cynomolgus  
              应用 : ELISA  
                11057-RP01-400
                11057-RP01-200
                11057-RP01-100
                400 µg 
                200 µg 
                100 µg 
                Add to Cart
                反应性: Cynomolgus  
                应用 : ELISA  
                  11057-RP02-50
                  11057-RP02-200
                  11057-RP02-100
                  50 µg 
                  200 µg 
                  100 µg 
                  Add to Cart

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                  IL13/IL-13 cdna-clone 研究背景

                  Interleukin 13 (IL-13) is a single-chain glycosylated polypeptide, which belongs to the IL-13/IL-4 family. IL-13 protein is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL-13 exerts its effects through a multi-subunit receptor comprising the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains (IL-13 Rα1 and IL-13 Rα2). As a cytokine, IL-13 protein is critical in regulating inflammatory, immune responses and diseases. In addition, it inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity. IL-13 protein and antibody is more importantly implicated as a central mediator of immunoregulatory processes in various cell types.

                  Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

                  大鼠 IL13/IL-13 cdna-clone 参考资料
                • Junttila IS, et al. (2008) Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Ralpha, IL-13Ralpha1, and gammac regulates relative cytokine sensitivity. J Exp Med. 205(11): 2595-608.
                • Shimamura T,et al. (2008) Novel role of IL-13 in fibrosis induced by nonalcoholic steatohepatitis and its amelioration by IL-13R-directed cytotoxin in a rat model. J Immunol. 181(7): 4656-65.
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