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人 CD10/Neprilysin 基因ORF全长cDNA克隆(表达载体), N-Flag 标签

产品数据评论实验方法
描述: Active  
表达宿主: Human Cells  
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10805-H01H-20
10805-H01H-10
20 µg 
10 µg 
Add to Cart
描述: Active  
表达宿主: Human Cells  
  • Slide 1
10805-HNCH-20
10805-HNCH-10
20 µg 
10 µg 
Add to Cart
描述: Active  
表达宿主: Human Cells  
  • Slide 1
10805-H07H-20
10805-H07H-10
20 µg 
10 µg 
Add to Cart
描述: Active  
表达宿主: Human Cells  
  • Slide 1
50218-M07H-20
50218-M07H-10
20 µg 
10 µg 
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表达宿主: Human Cells  
  • Slide 1
80288-R07H-20
80288-R07H-10
20 µg 
10 µg 
Add to Cart
表达宿主: Human Cells  
  • Slide 1
90177-C07H-20
90177-C07H-10
20 µg 
10 µg 
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反应性: Human  
应用 : FCM  
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10805-MM05-P-25
10805-MM05-P-100
25 Test 
100 Tests 
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反应性: Human  
应用 : IF  ICC/IF  
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100390-T02-50
100390-T02-200
100390-T02-100
50 µg 
200 µg 
100 µg 
Add to Cart
反应性: Human  
应用 : ELISA  
    10805-MM05-50
    10805-MM05-200
    10805-MM05-100
    50 µg 
    200 µg 
    100 µg 
    Add to Cart
    反应性: Mouse  
    应用 : ELISA  
      50218-T16-50
      50218-T16-200
      50218-T16-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      反应性: Rhesus  
      应用 : ELISA  WB  IHC-P  IP  
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      • Slide 1
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      90177-T60-50
      90177-T60-200
      90177-T60-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart

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      CD10/Neprilysin cdna-clone 研究背景

      The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 10 (CD10), also known as Neprilysin and neutral endopeptidase, is a member of the CD system. CD10 is a zinc-dependent metalloprotease enzyme that had function to degrade a number of small secreted peptides such as the amyloid beta peptide. It exist as a membrane-bound protein and have high concentration in kidney and lung tissues. Mutations in the CD10 gene can induce the familial forms of Alzheimer's disease, providing strong evidence for the protein's association with the Alzheimer's disease process. CD10 is also associated with other biochemical processes.

       CD10/Neprilysin cdna-clone 参考资料
    • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
    • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
    • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12
    • Dogan, et al. (2000) CD10 and BCL-6 Expression in Paraffin Sections of Normal Lymphoid Tissue and B-Cell Lymphomas. American Journal of Surgical Pathology. 24(6): 846-52.
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