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人 VEGFR3 / FLT4 基因全长ORF克隆 (表达载体), N端FLAG标签

产品数据评论实验方法
描述: Active  
表达宿主: Human Cells  
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10806-H08H-50
10806-H08H-100
50 µg 
100 µg 
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描述: Active  
表达宿主: Human Cells  
  • Slide 1
10806-H02H-50
10806-H02H-100
50 µg 
100 µg 
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描述: Active  
表达宿主: Human Cells  
  • Slide 1
50584-M08H-50
50584-M08H-100
50 µg 
100 µg 
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描述: Active  
表达宿主: Human Cells  
  • Slide 1
50584-M02H-50
50584-M02H-100
50 µg 
100 µg 
Add to Cart
反应性: Human  
应用 : ELISA  
    10806-RP01-400
    10806-RP01-100
    10806-RP01-200
     
    100 µg 
    200 µg 
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    反应性: Human  
    应用 : ELISA  
      10806-MM03-200
      10806-MM03-50
      10806-MM03-100
      200 µg 
      50 µg 
      100 µg 
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      反应性: Human  
      应用 : ELISA  WB  
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      10806-RP04-100
      10806-RP04-200
      10806-RP04-50
      100 µg 
      200 µg 
      50 µg 
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      反应性: Human  
      应用 : ELISA  
        10806-R005-100
        10806-R005-50
        100 µg 
        50 µg 
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        反应性: Human  
        应用 : ELISA  
          10806-T16-100
          10806-T16-50
          10806-T16-200
          100 µg 
          50 µg 
          200 µg 
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          反应性: Mouse  
          应用 : ELISA  
            50584-RP02-50
            50584-RP02-100
            50584-RP02-200
            50 µg 
            100 µg 
            200 µg 
            Add to Cart
            反应性: Mouse  
            应用 : ELISA  
              50584-R002-50
              50584-R002-100
              50 µg 
              100 µg 
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              VEGFR3/FLT-4  cdna-clone 研究背景

              Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belong to the class III subfamily of receptor tyrosine kinases (RTKs). The VEGFR3 protein is expressed mainly on lymphatic vessels but it is also up-regulated in tumor angiogenesis. Mutations in VEGFR3 have been identified in patients with primary lymphoedema. The VEGF-C/VEGF-D/VEGFR3 signaling pathway may provide a target for antilymphangiogenic therapy in prostate cancer, breast cancer, gastric cancer, lung cancer, non-small cell lung cancer (NSCLC), and so on.

              Human VEGFR3/FLT-4  cdna-clone 参考资料
            • Shushanov S, et al. (2000)VEGFc and VEGFR3 expression in human thyroid pathologies. Int J Cancer.86(1): 47-52.
            • Iljin K, et al. (2001) VEGFR3 gene structure, regulatory region, and sequence polymorphisms. FASEB J. 15(6): 1028-36.
            • Liu XE, et al. (2004) Expression and significance of VEGF-C and FLT-4 in gastric cancer. World J Gastroenterol. 10(3): 352-5.
            • Stearns ME, et al. (2004) Expression of a flt-4 (VEGFR3) splicing variant in primary human prostate tumors. VEGF D and flt-4t(Delta773-1081) overexpression is diagnostic for sentinel lymph node metastasis. Lab Invest. 84(6): 785-95.
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