Text Size:AAA

人 DSC2 基因ORF全长cDNA克隆(表达载体), N-Flag 标签

产品数据评论实验方法
表达宿主: Human Cells  
  • Slide 1
10809-H08H-50
10809-H08H-100
50 µg 
100 µg 
Add to Cart
表达宿主: Human Cells  
  • Slide 1
80266-R08H-50
80266-R08H-100
50 µg 
100 µg 
Add to Cart
表达宿主: Human Cells  
  • Slide 1
80266-R02H-50
80266-R02H-200
50 µg 
200 µg 
Add to Cart
反应性: Human  
应用 : ELISA  
    10809-MM06-50
    10809-MM06-200
    10809-MM06-100
    50 µg 
    200 µg 
    100 µg 
    Add to Cart
    反应性: Human  
    应用 : ELISA  
      10809-R521-50
      10809-R521-100
      50 µg 
      100 µg 
      Add to Cart
      反应性: Human  
      应用 : ELISA  
        10809-RP01-400
        10809-RP01-200
        10809-RP01-100
        400 µg 
        200 µg 
        100 µg 
        Add to Cart
        反应性: Human  
        应用 : ELISA  
          10809-MM04-50
          10809-MM04-200
          10809-MM04-100
          50 µg 
          200 µg 
          100 µg 
          Add to Cart
          反应性: Human  
          应用 : ELISA  IHC-P  
          • Slide 1
          • Slide 1
          10809-RP02-50
          10809-RP02-200
          10809-RP02-100
          50 µg 
          200 µg 
          100 µg 
          Add to Cart
          反应性: Human  
          应用 : ELISA  
            10809-R004-50
            10809-R004-100
            50 µg 
            100 µg 
            Add to Cart
            反应性: Rat  
            应用 : ELISA  
              80266-MM05-50
              80266-MM05-200
              80266-MM05-100
              50 µg 
              200 µg 
              100 µg 
              Add to Cart
              反应性: Rat  
              应用 : 
              • Slide 1
              80266-R003-50
              80266-R003-100
              50 µg 
              100 µg 
              Add to Cart
              反应性: Rat  
              应用 : ELISA  IHC-P  
              • Slide 1
              80266-T24-50
              80266-T24-200
              80266-T24-100
              50 µg 
              200 µg 
              100 µg 
              Add to Cart
              反应性: Rat  
              应用 : ELISA  
                80266-R023-50
                80266-R023-100
                50 µg 
                100 µg 
                Add to Cart
                反应性: Rat  
                应用 : ELISA  
                  80266-RP01-400
                  80266-RP01-200
                  80266-RP01-100
                  400 µg 
                  200 µg 
                  100 µg 
                  Add to Cart

                  DSC2 cDNARelated Products

                  Related Products

                  Featured Reagent Products

                  DSC2 cdna-clone 研究背景

                  DSC2 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. Like other desmocollins, murine DSC2 has two products, Dsc2a and Dsc2b, produced by alternative splicing of a 46 bp exon which encodes 11 COOH-terminal aa followed by an in-frame stop codon. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in DSC2 are associated with arrhythmogenic right ventricular dysplasia-11. DSC2 is Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. DSC2 may contribute to epidermal cell positioning by mediating differential adhesiveness between cells that express different isoforms.

                   DSC2 cdna-clone 参考资料
                • Nuber UA, et al. (1995) The widespread human desmocollin Dsc2 and tissue-specific patterns of synthesis of various desmocollin subtypes. Eur J Cell Biol. 66 (1): 69-74.
                • Marsden MD, et al. (1997) Cloning and transcriptional analysis of the promoter of the human type 2 desmocollin gene (DSC2). Gene. 186 (2): 237-47.
                • Greenwood MD, et al. (1997) Exon-intron organization of the human type 2 desmocollin gene (DSC2): desmocollin gene structure is closer to "classical" cadherins than to desmogleins. Genomics. 44 (3): 330-5.
                • 请注意:所有产品都是“仅用于科研,而不能用于诊断或治疗用途”