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人 CR2 / CD21 基因全长ORF克隆 (表达载体), N端FLAG标签

产品数据评论实验方法
描述: Active  
表达宿主: Human Cells  
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10811-H08H-50
10811-H08H-100
50 µg 
100 µg 
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反应性: Human  
应用 : ELISA  
    10811-MM11-100
    10811-MM11-200
    10811-MM11-50
    100 µg 
    200 µg 
    50 µg 
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    反应性: Human  
    应用 : ELISA  
      10811-RP01-400
      10811-RP01-100
      10811-RP01-200
       
      100 µg 
      200 µg 
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      反应性: Human  
      应用 : ELISA  WB  IHC-P  IP  
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      10811-RP02-200
      10811-RP02-50
      10811-RP02-100
      200 µg 
      50 µg 
      100 µg 
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      反应性: Human  
      应用 : ELISA  IHC-P  
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      10811-R005-50
      10811-R005-100
      50 µg 
      100 µg 
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      CD21 ELISA配对抗体

      检测限: 62.5 pg/ml
      SEK10811-5
      SEK10811-15
      5 Plates 
      15 Plates 
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      检测限: 31.25 pg/ml
      SEKA10811-5
      SEKA10811-15
      5 Plates 
      15 Plates 
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      CD21 cdna-clone 研究背景

      The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD21, also known as Complement component (3d / Epstein Barr virus) receptor 2 and CR2, is a member of the CD system and is a protein involved in complement system. CD21 is present on all mature B-cells and some T-cells and follicular dendritic cells. CD21 on mature B-cells form a complex called the B cell receptor complex with two other membrane proteins, CD19 and CD81. CD21 has a function in the complement system through serving as the cellular receper specific for ligands such as C3 and C4 which can be attached to foreign macromolecules in order to remove or uptake them. This results in B-cells having enhanced response to the antigen.

      Human CD21 cdna-clone 参考资料
    • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
    • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
    • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
    • Joseph M, et al. (1989) Structure and Function of the Complement Receptors, CR1 (CD35) and CR2 (CD21). Advanced in immunology. 46: 183-219.
    • Aubry JP, et al. (1992) CD21 is a ligand for CD23 and regulates IgE production. Nature 358: 505 - 7.
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