Anti-Cyclophilin A Antibody (Rabbit Polyclonal 抗体) 产品信息
Anti-Cyclophilin A Antibody
Reacts with: Mouse
Mouse Cyclophilin A
Recombinant Mouse Cyclophilin A / PPIA protein (Catalog#50296-M08E)
Produced in rabbits immunized with purified, recombinant Mouse Cyclophilin A / PPIA (rM Cyclophilin A / PPIA; Catalog#50296-M08E; NP_032933.1; Met 1-Leu 164). Cyclophilin A / PPIA specific IgG was purified by Mouse Cyclophilin A / PPIA affinity chromatography.
Polyclonal Rabbit IgG
Protein A & Antigen Affinity
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Anti-Cyclophilin A Antibody (Rabbit Polyclonal 抗体) 经验证的应用
Please Note: Optimal concentrations/dilutions should be determined by the end user.
Peptidyl-prolyl cis-trans isomerase A, also known as PPIase A, Rotamase A, Cyclophilin A, Cyclosporin A-binding protein, PPIA and CYPA, is a cytoplasm protein which belongs to thecyclophilin-type PPIase family and PPIase A subfamily. Cyclophilins (CyPs) are a family of proteins found in organisms ranging from prokaryotes to humans. These molecules exhibit peptidyl-prolyl isomerase activity, suggesting that they influence the conformation of proteins in cells. PPIA / Cyclophilin A accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIA / Cyclophilin A is secreted by vascular smooth muscle cells in response to inflammatory stimuli, and could thus contribute to atherosclerosis. It is not essential for mammalian cell viability. PPIA / Cyclophilin A can interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.