Integrin beta 3 cDNA ORF Clone, Rhesus, N-DDK (Flag®) tag

Integrins containing the beta(3) subunit are key players in tumor growth and metastasis.ITGB3 plays an important role in ROS-induced migration and invasion in Colorectal cancer (CRC).ITGB3 is translationally activated in hypoxia and regulates malignant features, including epithelial-mesenchymal transition and cell migration, through the TGF-beta pathway, revealing a novel angle for the treatment of therapy-resistant hypoxic tumours.Bioinformatic algorithms and luciferase reporter assays revealed that integrin beta3 (ITGB3) is a direct target of miR-3a-5p.

integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)

• Cardiovascular>>Angiogenesis>>Adhesion Molecules in Angiogenesis>>Integrin>>Alpha Integrin
• Cardiovascular>>Angiogenesis>>Adhesion Molecules in Angiogenesis>>Integrin>>Beta Integrin
• Microbiology>>Pathogenic microorganism>>viruses>>Animal virus>>RNA virus>>-ssRNA virus>>Bunyaviridae>>Hantaan virus (HTNV)>>HTNV infection associated>>HTNV host receptor
• Cardiovascular>>Atherosclerosis>>Hypertension>>Vascular remodelling>>Integrins in Vascular remodelling
• Cancer>>Signal Transduction>>ITIM/ITAM Immunoreceptors and Related Molecules
• Immunology>>Cluster of Differentiation (CD)>>Monocyte/Macrophage CD Antigen>>Macrophage Marker CD Antigen
• Immunology>>Innate Immunity>>Monocytes/Macrophages>>Macrophage Markers
• Stem Cells>>Hematopoietic Progenitors>>Myeloid>>Mast Cell Lineage
• Developmental Biology>>Embryogenesis>>Germ Layer Formation>>Mesoderm Marker
• Immunology>>Innate Immunity>>Monocytes/Macrophages>>Monocyte Markers
• Cardiovascular>>Blood>>Platelet
• Cardiovascular>>Atherosclerosis>>Thrombosis>>Platelets
• Stem Cells>>Hematopoietic Progenitors>>Myeloid>>Thrombocytic Lineage
• Microbiology>>Pathogenic microorganism>>viruses>>Animal virus>>Virus infection associated>>Virus host receptor>>WNV host receptor