• Cutting-edge technologies
• Most reliable partner
• Unmatched experience:>10,000 Mabs,>6000 Proteins
• Superior quality of products & services
• Unmatched speed of production
• Unmatched cost-saving
IgG-Fc-fusion-tag (Fc-chimeric protein) has been widely used in recombinant protein expression and production. The Fc-fusion-tag allows simple and efficient affinity purification of the tagged protein using protein A or protein G affinity chromatography. The Fc-fusion-tag (Fc-chimeric) also can be used for detection in western blot, ELISA assay by using commercially available antibodies and ELISA kits. The antibody Fc-region is typically fused to the C-terminus of protein and it is mostly used in mammalian cell expression system. The addition of the IgG-Fc could also increase protein solubility and expression yield sometimes. Due to the nature of the antibody IgG-Fc, Fc-chimeric proteins are expressed as homodimer.
Sino Biological has successfully produced many proteins with the antibody IgG-Fc-tag. We are highly experienced in designing the Fc-tag according to the protein structure and handle any problems arising from protein purification process. Sino Biological has also developed its own protein A and protein G affinity purification resin. For more information about our Protein A and Protein G affinity resin, please refer to: Antibody Purification Resins.
Our track-records in the past seven years (2008-2014) on the successful production of over 5000 recombinant protein bulks and over 10,000 monoclonal antibodies have attracted top-10 multi-national pharmaceutical customers as well as small biotech companies worldwide through word-of-mouth, as we have not done much business development or advertisement in the past. In 2015, we are starting to promote our protein production services to all research institutions and companies worldwide, as we believe more customers can benefit greatly from our capacity and experience.
How to Submit a Request for Protein Production Service?
If you are interested in using our protein production services to support your antibody discovery and development program, please contact us by leaving an on-line message or send us your detailed request to CROfirstname.lastname@example.org. Based on the quantity and quality requirement of your request, a formal quote will be send back to you for your review, comment, and/or acceptance.