Description of Protein Production Service in E. coli.

Your Most Reliable & Cost-Effective Protein & Antibody R&D Partner

• Cutting-edge technologies
• Most reliable partner
• Unmatched experience:>10,000 Mabs,>6000 Proteins

• Superior quality of products & services
• Unmatched speed of production
• Unmatched cost-saving

Description of Protein Production Service in E. coli. Fermentation

E. coli. has been most widely used for the last three decades for recombinant protein expression and production in virtually all biological laboratories worldwide. It is simple to learn and master, and it is fairly cheap to produce proteins in this system. The downside is that because it is a micro-organism, it does not possess the same capability as Eukaryotic cells for protein glycosylation and other post-translational modifications. So it is mostly used for production of relatively small and simple proteins.

With continuous innovation and improvement in E. coli. expression, many proteins can be expressed as a soluble protein without the troubles to go through tedious protein refolding process. However, there are still many proteins that can only be expressed as inclusion body and have to be refolded into soluble and function forms.

Sino Biological has devoted significant resources in development of protein expression and production in E. coli. system. In the past couple of years (2008-2014), we have successfully produced over 1000 recombinant proteins using our E. coli. expression system. Many of these proteins are tough ones that cannot be produced effectively and economically in mammalian cells.

Our track-records in the past seven years (2008-2014) on the successful production of over 5000 recombinant protein bulks and over 10,000 monoclonal antibodies have attracted top-10 multi-national pharmaceutical customers as well as small biotech companies worldwide through word-of-mouth, as we have not done much business development or advertisement in the past. In 2015, we are starting to promote our protein production services to all research institutions and companies worldwide, as we believe more customers can benefit greatly from our capacity and experience.

How to Submit a Request for Protein Production Service?

If you are interested in using our protein production services to support your antibody discovery and development program, please contact us by leaving an on-line message or send us your detailed request to Based on the quantity and quality requirement of your request, a formal quote will be send back to you for your review, comment, and/or acceptance.

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