Overexpression of the glycosylated mucin-like protein CD24 is a driver for the tumorigenesis and metastasis of bladder tumours and is androgen dependent, according to a recent study. CD24 is a biomarker of tumour aggressiveness in many common human cancer types—roles for CD24 have been described in tumour cell proliferation, anchorage-dependent growth and metastatic progression—but it is rarely expressed in normal tissue.
Drug targets for cancer: CD24 research reagents
Other vital drug targets for cancer likeCD24:
Fenner A. Bladder cancer: Androgen-dependent CD24 regulates bladder cancer progression—a new role for antiandrogen therapy?[J]. Nature Reviews Urology, 2012, 9(12): 665-665.