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DUSP1  蛋白,抗体,试剂盒,cDNA克隆

DUSP1 相关研究领域

DUSP1 相关信号通路

    DUSP1 相关蛋白、抗体、cDNA基因、ELISA试剂盒

    DUSP1 相关蛋白、抗体、cDNA基因、ELISA试剂盒

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    DUSP1 概述&蛋白信息

    DUSP1 研究背景

    催化活性: Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate. {ECO:0000255|PROSITE-ProRule:PRU10044}.; [a protein]-serine/threonine phosphate + H(2)O = [a protein]-serine/threonine + phosphate.
    亚细胞定位: Nucleus {ECO:0000250}.
    组织特异性: Expressed at high levels in the lung, liver placenta and pancreas. Moderate levels seen in the heart and skeletal muscle. Lower levels found in the brain and kidney. {ECO:0000269|PubMed:8106404}.
    诱导: By oxidative stress and heat shock.
    翻译后修饰: Phosphorylation at Ser-359 and Ser-364 by MAPK1/ERK2 and MAPK3/ERK1 reduces its rate of degradation. {ECO:0000250}.
    相似的序列: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. {ECO:0000305}.; Contains 1 rhodanese domain. {ECO:0000255|PROSITE-ProRule:PRU00173}.; Contains 1 tyrosine-protein phosphatase domain. {ECO:0000305}.
    General information above from UniProt

    DUSP1 别称

    HVH1,MKP1,CL100,MKP-1,PTPN10, [homo-sapiens]
    erp,MKP1,mkp-1,3CH134,Ptpn16,U19515, [mus-musculus]

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