ALK-1 ELISA Kit, Human

Temporarily not available outside of China.The online Datasheet here is only a general version, for batch specific information please refer to the hard copy included in the product shipping package.

ALK-1 ELISA Kit, Human: 产品信息

产品名称
ALK-1 ELISA Kit, Human
检测原理
Solid Phase Sandwich ELISA (quantitative)
偶联物
HRP
检测样品
Serum
灵敏度
18.8 pg/mL
线性范围
31.25-2000 pg/mL
特异性
Recognizes both recombinant and natural Human ALK-1
干扰
Preparations of TGFB1、INHBA、TGFBR1、ACVR1、FKBP1A、TSC22D1、HSP90AA1、BAMBI、ENG and TGFB2 at 20 ng/mL in a mid-range recombinant human ALK1 control were assayed for interference. No significant interference was observed.
精密度
  Intra-assay Precision
Sample 1 2 3
N 20 20 20
Mean(pg/mL) 0.32 0.62 1.16
SD 0.01 0.03 0.08
CV(%) 3.7% 5.1% 6.5%
  Inter-assay Precision
Sample 1 2 3
N 20 20 20
Mean(pg/mL) 0.34 0.59 1.21
SD 0.03 0.07 0.07
CV(%) 8.2% 11.1% 6.1%
回收率
The recovery of Human ACVRL1 spiked to different levels throughout the range of the assay in related matrices was evaluated.
Sample
serum (n=3)
Average % Recovery
82
Range
79-87%
线性关系
Serum
  Recovery of detected
1:2 99%
1:4 92%
1:8 86%
1:16 96%
ELISA 试剂盒(即用型)组分
1. 96 well microplate coated with Capture Antibody
2. Detection Antibody conjugated to HRP
3. Standards
4. Wash Buffer Concentrate
5. Dilution Buffer Concentrate
6. Sample Dilution Buffer Concentrate
7. Color Reagent A
8. Color Reagent B
9. Stop Solution
产品概述
This ALK-1 ELISA Kit, Human is an enzyme-linked immunosorbent assay for the quantitative measurement of Human ALK-1 protein in Serum . It contains recombinant Human ALK-1, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use.
运输方式
This ELISA Kit is shipped at ambient temperature.
储存条件
Unopened Kit: Store at 2 - 8℃
Opened/Reconstituted Reagents: Please refer to CoA

ALK-1 ELISA Kit, Human: 图片

This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
This assay recognizes both recombinant and natural human ALK1. The factors listed below were prepared at 50 ng/mL in dilution buffer and assayed for cross-reactivity. No cross-reactivity was observed.

ALK-1 ELISA Kit, Human: 别称

ACVRLK1 ELISA Kit, Human; ALK-1 ELISA Kit, Human; ALK1 ELISA Kit, Human; HHT ELISA Kit, Human; HHT2 ELISA Kit, Human; ORW2 ELISA Kit, Human; SKR3 ELISA Kit, Human; TSR-I ELISA Kit, Human

ALK-1 背景信息

Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. On ligand binding, a heteromeric receptor complex forms consisting of two type II and two type I transmembrane serine/threonine kinases. ACVRL1 protein is expressed in certain blood vessels of kidney, spleen, heart and intestine, serving as an important role during vascular development. Mutations in ACVRL1 gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2 and vascular disease.
全称
activin A receptor type II-like 1
参考文献
  • French Rendu-Osler network,et al. (2004) Molecular screening of ALK1/ACVRL1 and ENG genes in hereditary hemorrhagic telangiectasia in France. Hum Mutat. 23(4): 289-299.
  • Simon M, et al. (2006) Association of a polymorphism of the ACVRL1 gene with sporadic arteriovenous malformations of the central nervous system. J Neurosurg. 104(6): 945-9.
  • Argyriou L, et al. (2006) Novel mutations in the ENG and ACVRL1 genes causing hereditary hemorrhagic teleangiectasia. Int J Mol Med. 17(4):655-9.
添加购物车成功! 添加购物车失败!请再次尝试 正在更新购物车,请稍后 U.S.A.