CEACAM6 ELISA Kit, Human

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CEACAM6 ELISA Kit, Human: 产品信息

产品名称
CEACAM6 ELISA Kit, Human
检测原理
Solid Phase Sandwich ELISA (quantitative)
偶联物
HRP
检测样品
Serum
灵敏度
2.78 pg/mL
线性范围
15.63-1000 pg/mL
特异性
Recognizes both recombinant and natural Human CEACAM6
精密度
  Intra-assay Precision
Sample 1 2 3
N 20 20 20
Mean(pg/mL) 95.21 197.29 384.93
SD 3.67 8.75 21.56
CV(%) 3.9% 4.4% 5.6%
  Inter-assay Precision
Sample 1 2 3
N 20 20 20
Mean(pg/mL) 102.27 214.83 431.09
SD 5.41 17.75 26.98
CV(%) 5.3% 8.3% 6.3%
回收率
The recovery of Human CEACAM6 spiked to different levels throughout the range of the assay in related matrices was evaluated.
Sample
serum (n=3)
Average % Recovery
92
Range
88 -98%
线性关系
Serum
  Recovery of detected
1:2 87%
1:4 94%
1:8 102%
1:16 98%
ELISA 试剂盒(即用型)组分
1. 96 well microplate coated with Capture Antibody
2. Detection Antibody conjugated to HRP
3. Standards
4. Wash Buffer Concentrate
5. Dilution Buffer Concentrate
6. Color Reagent A
7. Color Reagent B
8. Stop Solution
产品概述
This CEACAM6 ELISA Kit, Human is an enzyme-linked immunosorbent assay for the quantitative measurement of Human CEACAM6 protein in Serum . It contains recombinant Human CEACAM6, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use.
运输方式
This ELISA Kit is shipped at ambient temperature.
储存条件
Unopened Kit: Store at 2 - 8℃
Opened/Reconstituted Reagents: Please refer to CoA

CEACAM6 ELISA Kit, Human: 图片

This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
This assay recognizes both recombinant and natural Human CEACAM6. The factors listed above were prepared at 50 ng/mL in dilution buffer and assayed for cross-reactivity. No cross-reactivity was observed.

CEACAM6 ELISA Kit, Human: 别称

CD66c ELISA Kit, Human; CEA ELISA Kit, Human; CEAL ELISA Kit, Human; NCA ELISA Kit, Human

CEACAM6 背景信息

Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6), also known as nonspecific crossreacting antigen (NCA) and CD66c, is one of seven human CEACAM family members within the immunoglobulin superfamily. It s a glycosylphosphatidylinositol-linked immunoglobulin superfamily member that is overexpressed in a variety of human cancers, including colon, breast and lung and is associated with tumourigenesis, tumour cell adhesion, invasion and metastasis. CEACAM6 is a unique mediator of migration and invasion of drug resistant oestrogen-deprived breast cancer cells, and this protein could be an important biomarker of metastasis. CEACAM6 is expressed by granulocytes and their progenitors. It is also expressed by epithelia of various organs and is upregulated in pancreatic and colon adenocarcinomas, as well as hyperplastic polyps. Resistance to adhesion-related apoptosis in tumor cells is conferred in the condition of CEACAM6 overexpression.
全称
carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
参考文献
  • Duxbury MS, et al. (2004) Overexpression of CEACAM6 promotes insulin-like growth factor I-induced pancreatic adenocarcinoma cellular invasiveness. Oncogene. 23(34): 5834-42.
  • Lewis-Wambi JS, et al. (2008) Overexpression of CEACAM6 promotes migration and invasion of oestrogen-deprived breast cancer cells. Eur J Cancer. 44(12): 1770-9.
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