Her2/ERBB2 ELISA Kit, Human

Temporarily not available outside of China.The online Datasheet here is only a general version, for batch specific information please refer to the hard copy included in the product shipping package.

Her2/ERBB2 ELISA Kit, Human: 产品信息

产品名称
Her2/ERBB2 ELISA Kit, Human
检测原理
Solid Phase Sandwich ELISA (quantitative)
偶联物
HRP
检测样品
Serum
灵敏度
7 pg/mL
线性范围
62.5-4000 pg/mL
特异性
Recognizes both recombinant and natural Human Her2/ERBB2
精密度
  Intra-assay Precision
Sample 1 2 3
N 20 20 20
Mean(pg/mL) 0.42 0.84 1.74
SD 0.01 0.02 0.05
CV(%) 2.4% 2.9% 3.0%
  Inter-assay Precision
Sample 1 2 3
N 20 20 20
Mean(pg/mL) 0.46 0.92 1.95
SD 0.04 0.08 0.16
CV(%) 9.0% 9.1% 8.4%
回收率
The recovery of Human ERBB2 spiked to different levels throughout the range of the assay in related matrices was evaluated.
Sample
serum (n=4)
Average % Recovery
90
Range
86 -92%
线性关系
Serum
  Recovery of detected
1:2 93%
1:4 93%
1:8 93%
1:16 81%
ELISA 试剂盒(即用型)组分
1. 96 well microplate coated with Capture Antibody
2. Detection Antibody conjugated to HRP
3. Standards
4. Wash Buffer Concentrate
5. Dilution Buffer Concentrate
6. Color Reagent A
7. Color Reagent B
8. Stop Solution
产品概述
This Her2/ERBB2 ELISA Kit, Human is an enzyme-linked immunosorbent assay for the quantitative measurement of Human Her2/ERBB2 protein in Serum . It contains recombinant Human Her2/ERBB2, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use.
运输方式
This ELISA Kit is shipped at ambient temperature.
储存条件
Unopened Kit: Store at 2 - 8℃
Opened/Reconstituted Reagents: Please refer to CoA

Her2/ERBB2 ELISA Kit, Human: 图片

This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
This assay recognizes both recombinant and natural Human ErbB2. The factors listed above were prepared at 1250 ng/mL in dilution buffer and assayed for cross-reactivity. No cross-reactivity was observed.

Her2/ERBB2 ELISA Kit, Human: 别称

CD340 ELISA Kit, Human; ENV ELISA Kit, Human; ENVW ELISA Kit, Human; ERVWE1 ELISA Kit, Human; HER-2 ELISA Kit, Human; HER-2/neu ELISA Kit, Human; HER2 ELISA Kit, Human; HERV-7q ELISA Kit, Human; HERV-W-ENV ELISA Kit, Human; HERV7Q ELISA Kit, Human; HERVW ELISA Kit, Human; HERVWENV ELISA Kit, Human; MLN 19 ELISA Kit, Human; MLN19 ELISA Kit, Human; NEU ELISA Kit, Human; NGL ELISA Kit, Human; TKR1 ELISA Kit, Human

Her2/ERBB2 背景信息

Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand binding and enhances kinase-mediated activation of downstream molecules. HER2 plays a key role in development, cell proliferation and differentiation. HER2 gene has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on.
全称
erb-b2 receptor tyrosine kinase 2
参考文献
  • Krawczyk N, et al. (2009) HER2 status on persistent disseminated tumor cells after adjuvant therapy may differ from initial HER2 status on primary tumor. Anticancer Res. 29(10): 4019-24.
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