Anti-GBA3 Antibody

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Anti-GBA3 Antibody (Rabbit Monoclonal 抗体) 产品信息

产品名称
Anti-GBA3 Antibody
经验证的应用
ELISA
交叉反应
Reacts with: Human
特异性
Human GBA3
免疫原
Recombinant Human GBA3 protein (Catalog#11593-H08B)
制备方法
This antibody was obtained from a rabbit immunized with purified, recombinant Human GBA3 (rh GBA3; Catalog#11593-H08B; NP_066024.1; Met 1-Leu 469).
来源
Monoclonal Rabbit IgG Clone #019
纯化
Protein A
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-GBA3 Antibody (Rabbit Monoclonal 抗体) 经验证的应用

应用 推荐稀释比/用量
ELISA 1:5000-1:10000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-GBA3 Antibody: 别称

Anti-CBG Antibody; Anti-CBGL1 Antibody; Anti-GBA3 Antibody; Anti-GLUC Antibody; Anti-KLrP Antibody; Anti-MGC104276 Antibody; Anti-MGC126878 Antibody

GBA3 背景信息

Cytosolic beta-glucosidase, also known as Cytosolic beta-glucosidase-like protein 1, GBA3, CBG and CBGL1 is a cytoplasm protein which belongs to theglycosyl hydrolase 1 family and Klotho subfamily. GBA3 / CBGL1 is a glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. GBA3 / CBGL1 is present in small intestine (at protein level). GBA3 / CBGL1 is expressed in liver, small intestine, colon, spleen and kidney. GBA3 / CBGL1 is down-regulated in renal cell carcinomas and hepatocellular carcinomas. GBA3 / CBGL1 is able to hydrolyze a broad variety of glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens. GBA3 / CBGL1 possesses beta-glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide.
全称
glucosidase, beta, acid 3 (gene/pseudogene)
参考文献
  • Yahata K., et al.,(2000), Molecular cloning and expression of a novel klotho-related protein. J. Mol. Med. 78:389-394.
  • de Graaf M., et al., (2001), Cloning and characterization of human liver cytosolic beta-glycosidase.Biochem. J. 356:907-910.
  • Berrin J.-G., et al.,(2002), Functional expression of human liver cytosolic beta-glucosidase in Pichia pastoris. Insights into its role in the metabolism of dietary glucosides.Eur. J. Biochem. 269:249-258.
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