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 KLK13/Kallikrein 13  抗体

All KLK13 Reagents

KLK13/Kallikrein 13
反应性: Human  
应用 : 
10199-MM06-50
10199-MM06-200
10199-MM06-100
10199-MM06-1
50 µg 
200 µg 
100 µg 
1 mg 
Add to Cart
    反应性: Human  
    应用 : ELISA  
    10199-RP01-400
    10199-RP01-200
    10199-RP01-100
    400 µg 
    200 µg 
    100 µg 
    Add to Cart
      反应性: Human  
      应用 : ELISA  
      10199-MM01-50
      10199-MM01-200
      10199-MM01-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
        反应性: Human  
        应用 : ELISA  
        10199-R001-50
        10199-R001-100
        50 µg 
        100 µg 
        Add to Cart
          反应性: Human  
          应用 : ELISA  
          10199-RP02-50
          10199-RP02-200
          10199-RP02-100
          50 µg 
          200 µg 
          100 µg 
          Add to Cart
            反应性: Human  
            应用 : ELISA  
            10199-T16-50
            10199-T16-200
            10199-T16-100
            50 µg 
            200 µg 
            100 µg 
            Add to Cart
              10199-H08HL-300 

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              KLK13/Kallikrein 13 相关研究领域

              KLK13/Kallikrein 13 相关信号通路

                KLK13/Kallikrein 13 相关蛋白、抗体、cDNA基因、ELISA试剂盒

                KLK13/Kallikrein 13 相关蛋白、抗体、cDNA基因、ELISA试剂盒

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                KLK13/Kallikrein 13 概述&蛋白信息

                KLK13/Kallikrein 13 研究背景

                基因概述: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This KLK13 gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. An additional transcript variant has been identified, but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]
                General information above from NCBI
                亚细胞定位: Secreted {ECO:0000305}.
                组织特异性: Expressed in prostate, breast, testis and salivary gland.
                相似的序列: Belongs to the peptidase S1 family. Kallikrein subfamily. {ECO:0000255|PROSITE-ProRule:PRU00274}.; Contains 1 peptidase S1 domain. {ECO:0000255|PROSITE-ProRule:PRU00274}.
                General information above from UniProt

                Tissue kallikrein 13 (hK13), also known as KLK-L4 (kallikrein-like gene 4), is a member of the human tissue kallikrein family of serine proteases having diverse physiological functions in many tissues. The KLK13 gene resides on chromosome 19q13.3-4 along with other 14 members in a gene cluster and shares a high degree of homology. KLK13 is a trypsin-like, secreted serine protease expressed specifically in the testicular tissue including prostate, salivary gland, breast, and testis. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and may play a role in metastasis. KLK13 may be involved in the pathogenesis and/or progression of breast and ovary cancers, and is regarded as a novel cancer biomarker. In addition, KLK13 interacts and forms complexes with several serum protease inhibitors, such as alpha2-macroglobulin, and its expression is regulated by steroid hormones.

                KLK13/Kallikrein 13 别称

                KLK13/Kallikrein 13 相关文献

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