Anti-MINA/MINA53 Magnetic Beads Immunoprecipitation (IP) Kit

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Anti-MINA/MINA53 磁珠免疫沉淀(IP)试剂盒产品组分

Components Storage
Anti-MINA/MINA53 Magnetic Beads1,3 2-8℃ for 12 months
NP40 Cell Lysis Buffer2 -20℃ for 12 months
5×TBST(pH7.4)  
1×TBST(pH7.4)  
ddH2O  
Alkaline Elution Buffer 2-8℃ for 12 months
Acidity Elution Buffer 2-8℃ for 12 months
Neutralization Buffer 2-8℃ for 12 months

【1】The IP KIT contains anti-MINA/MINA53 magnetic Beads (2 mg/mL) in phosphate buffered saline (PBS, pH 7.4) with sodium azide (0.1%).

【2】Using NP-40 cell lysate buffer in the kit is required,otherwise,the magnetic beads may be precipitated.

【3】Shipping: Magnetic Beads kits are shipped at ambient temperature in which magnetic beads are provided in liquid buffer.

Anti-MINA/MINA53 磁珠免疫沉淀(IP)试剂盒产品描述

The Anti-MINA/MINA53 magnetic Beads, conjugated with Anti-MINA/MINA53 antibody, are used for immuneprecipitation (IP) of MINA/MINA53 proteins which expressed in vitro expression systems. For IP, the beads are added to a sample containing MINA/MINA53 proteins to form a bead-protein complex. The complex is removed from the solution manually using a magnetic separator. The bound MINA/MINA53 proteins are dissociated from the magnetic beads using an elution buffer.

Anti-MINA/MINA53 磁珠免疫沉淀(IP)试剂盒抗体信息

抗体
Anti-MINA/MINA53 Antibody, Rabbit Polyclonal(203349-T38)
免疫原
E. coli-derived Human MINA/MINA53/RIOX2 fragment
交叉反应
Human MINA/MINA53/RIOX2
来源
Polyclonal Human Rabbit IgG
制备方法
Produced in rabbits immunized with E. coli-derived Human MINA/MINA53/RIOX2 fragment, and purified by antigen affinity chromatography.
应用
Immunoprecipitation (IP), Minimum Protein Purification

Anti-MINA/MINA53 Magnetic Beads Immunoprecipitation (IP) Kit: 别称

Anti-MDIGALCAM Magnetic Beads-Immunoprecipitatiopn (IP) Kit; Anti-MINA53ALCAM Magnetic Beads-Immunoprecipitatiopn (IP) Kit; Anti-NO52ALCAM Magnetic Beads-Immunoprecipitatiopn (IP) Kit; Anti-ROXALCAM Magnetic Beads-Immunoprecipitatiopn (IP) Kit

MINA/MINA53 背景信息

RIOX2 (Ribosomal Oxygenase 2, also known as MINA) is a Protein Coding gene. The RIOX2 gene, located on 3q11.2, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. An important paralog of this gene is RIOX1. MINA is a c-Myc target gene that may play a role in cell proliferation or regulation of cell growth. RIOX2 is widely expressed in the thyroid, skin, and other tissues. Diseases associated with RIOX2 include Squamous Cell Carcinoma and Lung Cancer. Among its related pathways are Chromatin organization and Validated targets of C-MYC transcriptional activation. 222 organisms have orthologs with the human gene RIOX2.
全称
MYC induced nuclear antigen
参考文献
  • Zhou L, et al. (2019) Mina53 regulates the differentiation and proliferation of leukemia cells. Hematol Oncol 37 (4): 513-515.
  • Zhang Q, et al. (2020) Crispr-cas9 gene editing causes alternative splicing of the targeting mrna. Biochem Biophys Res Commun 528 (1): 54-61.
  • Xuan F, et al. (2018) Mina53 deficiency leads to glioblastoma cell apoptosis via inducing DNA replication stress and diminishing DNA damage response. Cell Death Dis 9 (11): 1062.
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