KIR2DL5 (蛋白 | 抗体 | cDNA 克隆 | ELISA 试剂盒)

All KIR2DL5 reagents are produced in house and quality controlled, including 13 KIR2DL5 Gene, 1 KIR2DL5 Lysate, 1 KIR2DL5 Protein. All KIR2DL5 reagents are ready to use.

KIR2DL5 分子背景

The most recently described member of the KIR family, KIR2DL5, is represented in human populations by at least four gene variants, whose exons differ by two to eight nucleotides.KIR2DL5 (CD158f) is the most recently identified inhibitory member of human killer-cell Ig-like receptors (KIRs), which enable NK cells to sense self-HLA.KIR2DL5 is encoded by two paralogous genes displaying copy number variation and allelic polymorphism-KIR2DL5A and KIR2DL5B. Functional polymorphisms in both its promoter and its coding regions are critical for understanding the KIR2DL5 role in immunity and its importance for human health.