Integrin beta 3 cDNA ORF Clone, Mouse, C-HA tag

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Integrin beta 3 cDNA ORF Clone, Mouse, C-HA tag: 产品信息

基因
种属
Mouse
NCBI 参考序列号
基因长度
2364 bp
产品特征
Full length Clone DNA of Mouse integrin beta 3 with C terminal HA tag.
质粒
启动子
Enhanced CMV promoter
载体
标签序列
HA Tag Sequence: TATCCTTACGACGTGCCTGACTACGCC
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.
筛选
细菌筛选抗性
Kanamycin
细胞筛选抗性
Hygromycin
应用
Stable or Transient mammalian expression
储存 & 运输
运输方式
Each tube contains lyophilized plasmid.
储存条件
The lyophilized plasmid can be stored at ambient temperature for three months.

Integrin beta 3 cDNA ORF Clone, Mouse, C-HA tag: 别称

CD61 cDNA ORF Clone, Mouse; GP3A cDNA ORF Clone, Mouse; INGRB3 cDNA ORF Clone, Mouse

Integrin beta 3 背景信息

Integrins containing the beta(3) subunit are key players in tumor growth and metastasis.ITGB3 plays an important role in ROS-induced migration and invasion in Colorectal cancer (CRC).ITGB3 is translationally activated in hypoxia and regulates malignant features, including epithelial-mesenchymal transition and cell migration, through the TGF-beta pathway, revealing a novel angle for the treatment of therapy-resistant hypoxic tumours.Bioinformatic algorithms and luciferase reporter assays revealed that integrin beta3 (ITGB3) is a direct target of miR-3a-5p.
全称
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
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