Asialoglycoprotein Receptor Matched ELISA Antibody Pair Set,Human

For the orders from outside of China: MOQ 15 plates, lead time: 2 weeks.
1/1
Price:
Size:
Number:

Asialoglycoprotein Receptor Matched ELISA Antibody Pair Set,Human 产品信息

产品名称
Asialoglycoprotein Receptor Matched ELISA Antibody Pair Set,Human
检测原理
Solid Phase Sandwich ELISA
特异性
Quantitative determination of Human Asialoglycoprotein Receptor
线性范围
39.06-2500 pg/mL
ELISA 抗体对套装(非即用型)组分
1. Capture Antibody 0.2 mg/mL of rabbit anti-ASGR1 monoclonal antibody (in PBS, pH 7.4). Dilute to a working concentration of 2 μg/mL in PBS before coating. (Catalog: # 10773-R021)
2. Detection Antibody 0.2 mg/mL rabbit anti-ASGR1 monoclonal antibody conjugated to horseradish-peroxidase (HRP) (in PBS, 50 % HRP-Protector, pH 7.4, store at 4℃). Dilute to working concentration of 0.5 μg/mL in detection antibody dilution buffer before use. (Catalog: # 10773-R024)
3. Standard Each vial contains 150 ng of recombinant ASGR1. Reconstitute with 1 mL detection antibody dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in sample dilution buffer, and a high standard of 2.5 ng/mL is recommended.
产品概述
This Asialoglycoprotein Receptor Matched ELISA Antibody Pair Set,Human is a solid phase sandwich ELISA for quantitative determination of Human Asialoglycoprotein Receptor . It contains Human Asialoglycoprotein Receptor capture antibody, Human Asialoglycoprotein Receptor detector antibody (HRP) and a highly purified HEK293-expressed recombinant Human Asialoglycoprotein Receptor protein. This Pair Set is at affordable price for researchers.
运输方式
This Matched ELISA Antibody Pair Set is shipped at ambient temperature.
储存条件
Capture Antibody: Aliquot and store at -20℃ to -80℃ for up to 6 months from date of receipt. Avoid repeated freeze-thaw cycles.
Detection Antibody: Store at 4℃ and protect it from prolonged exposure to light for up to 6 months from date of receipt. DO NOT FREEZE!
Standard: Store lyophilized standard at -20℃ to -80℃ for up to 6 months from date of receipt. Aliquot and store the reconstituted Standard at -80℃ for up to 1 month. Avoid repeated freeze-thaw cycles.

Asialoglycoprotein Receptor Matched ELISA Antibody Pair Set,Human 图片

Asialoglycoprotein Receptor Matched ELISA Antibody Pair Set,Human: 别称

ASGPR Matched ELISA Antibody Pair Set, Human; ASGPR1 Matched ELISA Antibody Pair Set, Human; CLEC4H1 Matched ELISA Antibody Pair Set, Human; HL-1 Matched ELISA Antibody Pair Set, Human

Asialoglycoprotein Receptor 背景信息

The asialoglycoprotein receptor (ASGPR), an endocytotic cell surface receptor expressed by hepatocytes, is triggered by triantennary binding to galactose residues of macromolecules such as asialoorosomucoid (ASOR). ASGPR belongs to the long-form subfamily of the C-type/Ca2+ dependent lectin family. It is a complex of two noncovalently-linked and highly homologous subunits, a major 42 kDa glycoprotein ASGPR1(MHL-1) and a minor 51 kDa glycoprotein ASGR2 (MHL-2). ASGPR1 is synthesized as a type II transmembrane protein that contains a cytosolic N-terminal domain, a single transmembrane segment, and an extracellular domain which contains two important structural regions. The first is a stalk domain that contributes to noncovalent oligomerization, and the second is a Ca2+-dependent carbohydrate binding domain at the very C-terminus that is unusually stabilized by three ions. The research regarded that ASGPR1 could be targeted for anti- hepatitis B virus (HBV) drug development.
全称
asialoglycoprotein receptor 1
参考文献
  • Yang J, et al. (2006) Antisense oligonucleotides targeted against asialoglycoprotein receptor 1 block human hepatitis B virus replication. J Viral Hepat. 13(3): 158-65.
  • Li Y, et al. (2008) Targeted delivery of macromolecular drugs: asialoglycoprotein receptor (ASGPR) expression by selected hepatoma cell lines used in antiviral drug development. Curr Drug Deliv. 5(4): 299-302.
添加购物车成功! 添加购物车失败!请再次尝试 正在更新购物车,请稍后 U.S.A.