Galectin 3/LGALS3 Matched ELISA Antibody Pair Set,Human

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Galectin 3/LGALS3 Matched ELISA Antibody Pair Set,Human 产品信息

产品名称
Galectin 3/LGALS3 Matched ELISA Antibody Pair Set,Human
检测原理
Solid Phase Sandwich ELISA
特异性
Quantitative determination of Human Galectin 3/LGALS3
线性范围
3.91-250 pg/mL
ELISA 抗体对套装(非即用型)组分
1. Capture Antibody 0.5 mg/mL of mouse anti-Human Galectin-3/LGALS3 monoclonal antibody (in PBS, pH 7.4). Dilute to a working concentration of 2 μg/mL in PBS before coating. (Catalog: # 10289-MM05)
2. Detection Antibody 0.2 mg/mL of rabbit anti-Human Galectin-3/LGALS3 monoclonal antibody conjugated to horseradish-peroxidase (HRP) (in PBS, 50 % HRP-Protector, pH 7.4, store at 4℃). Dilute to working concentration of 0.25 μg/mL in detection antibody dilution buffer before use. (Catalog: # 10289-R179)
3. Standard Each vial contains 30 ng of recombinant Human Galectin-3/LGALS3. Reconstitute with 1 mL detection antibody dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in sample dilution buffer, and a high standard of 250 pg/mL is recommended.
产品概述
This Galectin 3/LGALS3 Matched ELISA Antibody Pair Set,Human is a solid phase sandwich ELISA for quantitative determination of Human Galectin 3/LGALS3 . It contains Human Galectin 3/LGALS3 capture antibody, Human Galectin 3/LGALS3 detector antibody (HRP) and a highly purified E. coli-expressed recombinant Human Galectin 3/LGALS3 protein. This Pair Set is at affordable price for researchers.
运输方式
This Matched ELISA Antibody Pair Set is shipped at ambient temperature.
储存条件
Capture Antibody: Aliquot and store at -20℃ to -80℃ for up to 6 months from date of receipt. Avoid repeated freeze-thaw cycles.
Detection Antibody: Store at 4℃ and protect it from prolonged exposure to light for up to 6 months from date of receipt. DO NOT FREEZE!
Standard: Store lyophilized standard at -20℃ to -80℃ for up to 6 months from date of receipt. Aliquot and store the reconstituted Standard at -80℃ for up to 1 month. Avoid repeated freeze-thaw cycles.

Galectin 3/LGALS3 Matched ELISA Antibody Pair Set,Human 图片

Galectin 3/LGALS3 Matched ELISA Antibody Pair Set,Human: 别称

CBP35 Matched ELISA Antibody Pair Set, Human; GAL3 Matched ELISA Antibody Pair Set, Human; GALBP Matched ELISA Antibody Pair Set, Human; GALIG Matched ELISA Antibody Pair Set, Human; L31 Matched ELISA Antibody Pair Set, Human; LGALS2 Matched ELISA Antibody Pair Set, Human; MAC2 Matched ELISA Antibody Pair Set, Human

Galectin 3/LGALS3 背景信息

LGALS3 (Galectin 3) is a Protein Coding gene. This gene encodes a member of the galectin family of carbohydrate-binding proteins. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. LGALS3 is a beta-galactoside-binding lectin and plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion, and T-cell regulation. LGALS3 has an important role in tumor progression through inhibition of apoptosis. LGALS3 expression is associated with neoplastic transformation and with differentiation of monocytes to macrophages. Elevated expression of LGALS3 has been demonstrated in the synovium of rheumatoid arthritis (RA). Diseases associated with LGALS3 include Follicular Adenoma and Papillary Carcinoma.
全称
lectin, galactoside-binding, soluble, 3
参考文献
  • Dumic J, et al. (2006) Galectin-3: an open-ended story. Biochim Biophys Acta. 1760(4): 616-35.
  • Sharma UC, et al. (2004) Galectin-3 marks activated macrophages in failure-prone hypertrophied hearts and contributes to cardiac dysfunction. Circulation. 110(19): 3121-8.
  • Yan YP, et al. (2009) Galectin-3 mediates post-ischemic tissue remodeling. Brain Res. 1288: 116-24.
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