JAM-A/Junctional Adhesion Molecule A Matched ELISA Antibody Pair Set,Human

For the orders from outside of China: MOQ 15 plates, lead time: 2 weeks.
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JAM-A/Junctional Adhesion Molecule A Matched ELISA Antibody Pair Set,Human 产品信息

产品名称
JAM-A/Junctional Adhesion Molecule A Matched ELISA Antibody Pair Set,Human
检测原理
Solid Phase Sandwich ELISA
特异性
Quantitative determination of Human JAM-A/Junctional Adhesion Molecule A
线性范围
7.8-500 pg/mL
ELISA 抗体对套装(非即用型)组分
1. Capture Antibody 0.5 mg/mL of mouse anti-Human Junctional Adhesion Molecule A / JAM-A monoclonal antibody (in PBS, pH 7.4). Dilute to a working concentration of 2 μg/mL in PBS before coating. (Catalog: # 10198-MM08)
2. Detection Antibody 0.1 mg/mL of mouse anti-Human Junctional Adhesion Molecule A / JAM-A monoclonal antibody conjugated to horseradish-peroxidase (HRP) (in PBS, 50 % HRP-Protector, pH 7.4, store at 4℃). Dilute to working concentration of 0.4 μg/mL in detection antibody dilution buffer before use. (Catalog: # 10198-MM02)
3. Standard Each vial contains 10 ng of recombinant Human Junctional Adhesion Molecule A / JAM-A. Reconstitute with 1 mL detection antibody dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in sample dilution buffer, and a high standard of 500 pg/mL is recommended.
产品概述
This JAM-A/Junctional Adhesion Molecule A Matched ELISA Antibody Pair Set,Human is a solid phase sandwich ELISA for quantitative determination of Human JAM-A/Junctional Adhesion Molecule A . It contains Human JAM-A/Junctional Adhesion Molecule A capture antibody, Human JAM-A/Junctional Adhesion Molecule A detector antibody (HRP) and a highly purified HEK293-expressed recombinant Human JAM-A/Junctional Adhesion Molecule A protein. This Pair Set is at affordable price for researchers.
运输方式
This Matched ELISA Antibody Pair Set is shipped at ambient temperature.
储存条件
Capture Antibody: Aliquot and store at -20℃ to -80℃ for up to 6 months from date of receipt. Avoid repeated freeze-thaw cycles.
Detection Antibody: Store at 4℃ and protect it from prolonged exposure to light for up to 6 months from date of receipt. DO NOT FREEZE!
Standard: Store lyophilized standard at -20℃ to -80℃ for up to 6 months from date of receipt. Aliquot and store the reconstituted Standard at -80℃ for up to 1 month. Avoid repeated freeze-thaw cycles.

JAM-A/Junctional Adhesion Molecule A Matched ELISA Antibody Pair Set,Human 图片

JAM-A/Junctional Adhesion Molecule A Matched ELISA Antibody Pair Set,Human: 别称

CD321 Matched ELISA Antibody Pair Set, Human; JAM Matched ELISA Antibody Pair Set, Human; JAM1 Matched ELISA Antibody Pair Set, Human; JAMA Matched ELISA Antibody Pair Set, Human; JCAM Matched ELISA Antibody Pair Set, Human; KAT Matched ELISA Antibody Pair Set, Human; PAM-1 Matched ELISA Antibody Pair Set, Human

JAM-A/Junctional Adhesion Molecule A 背景信息

Junctional adhesion molecule-A (JAM-A), also known as F11 receptor (F11R) or Cluster of Differentiation 321 (CD321), is a transmembrane protein expressed at tight junctions of epithelial and endothelial cells, as well as on circulating leukocytes. JAM-A protein serves as a serotype-independent receptor for mammalian orthoreoviruses (reoviruses). It is also a ligand for the integrin LFA1, involves in leukocyte transmigration. As a cell adhesion molecule of the immunoglobulin superfamily, JAM-A protein involves in platelet adhesion, secretion and aggregation, and plays a crucial role in inflammatory thrombosis and atherosclerosis. In addition, it may be a potential therapeutic target for breast cancer.
全称
F11 receptor
参考文献
  • Guglielmi KM, et al. (2007) Reovirus binding determinants in junctional adhesion molecule-A. J Biol Chem. 282(24): 17930-40.
  • Yeung D, et al. (2008) Decreased junctional adhesion molecule-A expression during blood-brain barrier breakdown. Acta Neuropathol. 115(6): 635-42.
  • Ong KL, et al. (2009) Elevated plasma level of soluble F11 receptor/junctional adhesion molecule-A (F11R/JAM-A) in hypertension. Am J Hypertens. 22(5): 500-5.
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