Parathyroid Hormone/PTH Matched ELISA Antibody Pair Set,Human

For the orders from outside of China: MOQ 15 plates, lead time: 2 weeks.
1/1
Price:
Size:
Number:

Parathyroid Hormone/PTH Matched ELISA Antibody Pair Set,Human 产品信息

产品名称
Parathyroid Hormone/PTH Matched ELISA Antibody Pair Set,Human
检测原理
Solid Phase Sandwich ELISA
特异性
Quantitative determination of Human Parathyroid Hormone/PTH
线性范围
312.5-20000 pg/mL
ELISA 抗体对套装(非即用型)组分
1. Capture Antibody 1 mg/mL of mouse anti-Human PTH/PTH1/Parathyroid Hormone monoclonal antibody (in PBS, pH 7.4). Dilute to a working concentration of 2 μg/mL in PBS before coating. (Catalog: # 13192-MM02)
2. Detection Antibody 0.2 mg/mL of rabbit anti-Human PTH/PTH1/Parathyroid Hormone polyclonal antibody conjugated to horseradish-peroxidase (HRP) (in PBS, 50 % HRP-Protector, pH 7.4, store at 4℃). Dilute to working concentration of 0.25 μg/mL in Dilution Buffer before use. (Catalog: # 13192-Pab)
3. Standard Each vial contains 380 ng of recombinant Human PTH/PTH1/Parathyroid Hormone. Reconstitute with 1 mL Dilution Buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in Dilution Buffer, and a high standard of 20000 pg/mL is recommended.
产品概述
This Parathyroid Hormone/PTH Matched ELISA Antibody Pair Set,Human is a solid phase sandwich ELISA for quantitative determination of Human Parathyroid Hormone/PTH . It contains Human Parathyroid Hormone/PTH capture antibody, Human Parathyroid Hormone/PTH detector antibody (HRP) and a highly purified E. coli-expressed recombinant Human Parathyroid Hormone/PTH protein. This Pair Set is at affordable price for researchers.
运输方式
This Matched ELISA Antibody Pair Set is shipped at ambient temperature.
储存条件
Capture Antibody: Aliquot and store at -20℃ to -80℃ for up to 6 months from date of receipt. Avoid repeated freeze-thaw cycles.
Detection Antibody: Store at 4℃ and protect it from prolonged exposure to light for up to 6 months from date of receipt. DO NOT FREEZE!
Standard: Store lyophilized standard at -20℃ to -80℃ for up to 6 months from date of receipt. Aliquot and store the reconstituted Standard at -80℃ for up to 1 month. Avoid repeated freeze-thaw cycles.

Parathyroid Hormone/PTH Matched ELISA Antibody Pair Set,Human 图片

Parathyroid Hormone/PTH Matched ELISA Antibody Pair Set,Human: 别称

PTH Matched ELISA Antibody Pair Set, Human; PTH1 Matched ELISA Antibody Pair Set, Human

Parathyroid Hormone/PTH 背景信息

Parathyroid hormone (PTH), parathormone or parathyrin, is secreted by the chief cells of the parathyroid glands as a polypeptide. PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Parathyroid hormone (PTH) has been proved to play a pivotal role in maintaining myocardial contractility as well as effective natriuresis, and possible pathogenic mechanisms contributing to heart failure secondary to hypocalcemia and hypoparathyroidism. With the increased population of preosteoblastic lineages and the osteoblastic activation, Parathyroid hormone (PTH) drives anabolism in bone. Experiments have recently reported that PTH affects bone cells in a dual pathway - mediating osteoblastic (preosteoblastic) activities or osteocytic synthesis of sclerostin. Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH), also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps.
全称
parathyroid hormone
参考文献
  • Bedi B, et al. (2012) Silencing of parathyroid hormone (PTH) receptor 1 in T cells blunts the bone anabolic activity of PTH. Proc Natl Acad Sci U S A. 109(12): 725-33.
  • Hasegawa T, et al. (2012) Parathyroid hormone as a Bone anabolic agent. Biological function of bone cells on the PTH-driven anabolic effect. Clin Calcium. 22(3): 373-9.
  • Ito M. Parathyroid hormone as a Bone anabolic agent. Effect of PTH on bone structural properties. Clin Calcium. 22(3): 335-41.
添加购物车成功! 添加购物车失败!请再次尝试 正在更新购物车,请稍后 U.S.A.