REG4 Matched ELISA Antibody Pair Set,Human

For the orders from outside of China: MOQ 15 plates, lead time: 2 weeks.
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REG4 Matched ELISA Antibody Pair Set,Human 产品信息

产品名称
REG4 Matched ELISA Antibody Pair Set,Human
检测原理
Solid Phase Sandwich ELISA
特异性
Quantitative determination of Human REG4
线性范围
3.91-250 pg/mL
ELISA 抗体对套装(非即用型)组分
1. Capture Antibody 0.3 mg/mL of mouse anti-REG4 monoclonal antibody. Dilute to a working concentration of 2 μg/mL in CBS before coating. (Catalog: # 11186-MM05)
2. Detection Antibody 0.5 mg/mL mouse anti-REG4 monoclonal antibody conjugated to horseradish-peroxidase (HRP). Dilute to working concentration of 0.5 μg/mL in detection antibody dilution buffer before use. (Catalog: # 11186-MM01)
3. Standard Each vial contains 14 ng of recombinant REG4. Reconstitute with 1 mL detection antibody dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in sample dilution buffer, and a high standard of 0.25 ng/mL is recommended.
产品概述
This REG4 Matched ELISA Antibody Pair Set,Human is a solid phase sandwich ELISA for quantitative determination of Human REG4 . It contains Human REG4 capture antibody, Human REG4 detector antibody (HRP) and a highly purified HEK293-expressed recombinant Human REG4 protein. This Pair Set is at affordable price for researchers.
运输方式
This Matched ELISA Antibody Pair Set is shipped at ambient temperature.
储存条件
Capture Antibody: Aliquot and store at -20℃ to -80℃ for up to 6 months from date of receipt. Avoid repeated freeze-thaw cycles.
Detection Antibody: Protect it from prolonged exposure to light. Aliquot and store at -20℃ to -80℃ and for up to 6 months from date of receipt. Avoid repeated freeze-thaw cycles.
Standard: Store lyophilized standard at -20℃ to -80℃ for up to 6 months from date of receipt. Aliquot and store the reconstituted Standard at -80℃ for up to 1 month. Avoid repeated freeze-thaw cycles.

REG4 Matched ELISA Antibody Pair Set,Human 图片

REG4 Matched ELISA Antibody Pair Set,Human: 别称

GISP Matched ELISA Antibody Pair Set, Human; REG-IV Matched ELISA Antibody Pair Set, Human; RELP Matched ELISA Antibody Pair Set, Human

REG4 背景信息

Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP, a member of the regenerating gene family belonging to the calcium (C-type) dependent lectin superfamily, has been found to be involved in malignancy in several different organs including the stomach, colorectum, pancreas and prostate. It is highly expressed in the gastrointestinal tract and markedly up-regulated in colon adenocarcinoma, pancreatic cancer, gastric adenocarcinoma, and inflammatory bowel disease. Expression of the Reg4 in different cell types has been associated with regeneration, cell growth and cell survival, cell adhesion and resistance to apoptosis. REG4 protein overexpression is associated with an unfavorable response to preoperative chemoradiotherapy and may be used as a predictive biomarker clinically. REG4 may play an important role in the development and progression of colorectal cancer, as well as in intestinal morphogenesis and epithelium restitution.
全称
regenerating islet-derived family, member 4
参考文献
  • Li FY, et al. (2010) RegIV expression showing specificity to gastrointestinal tract and its potential role in diagnosing digestive tract neuroendocrine tumor. J Zhejiang Univ Sci B. 11(4):258-66.
  • Rafa L, et al. (2010) REG4 acts as a mitogenic, motility and pro-invasive factor for colon cancer cells. Int J Oncol. 36(3): 689-98.
  • Hu G, et al. (2010) Purification of a bioactive recombinant human Reg IV expressed in Escherichia coli. Protein Expr Purif. 69(2): 186-90.
  • REG4 Is Highly Expressed in Mucinous Ovarian Cancer: A Potential Novel Serum Biomarker
    Author
    Lehtinen, L;Vesterkvist, P;Roering, P;Korpela, T;Hattara, L;Kaipio, K;Mpindi, JP;Hynninen, J;Auranen, A;Davidson, B;Haglund, C;Iljin, K;Grenman, S;Siitari, H;Carpen, O;
    Year
    2016
    Journal
    PLoS ONE
    Application
    ELISA (serum sample)
  • Prognostic and diagnostic value of REG4 serum and tissue expression in pancreatic ductal adenocarcinoma
    Author
    Saukkonen, K;Hagström, J;Mustonen, H;Lehtinen, L;Carpen, O;Andersson, LC;Seppänen, H;Haglund, C;
    Year
    2018
    Journal
    Tumour Biol.
    Application
    ELISA (serum)
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