ST2/IL-1 RL1 Matched ELISA Antibody Pair Set,Human
For the orders from outside of China: MOQ 15 plates, lead time: 2 weeks.The online Datasheet here is only a general version, for batch specific information please refer to the hard copy included in the product shipping package.
ST2/IL-1 RL1 Matched ELISA Antibody Pair Set,Human 产品信息
产品名称
ST2/IL-1 RL1 Matched ELISA Antibody Pair Set,Human
检测原理
Solid Phase Sandwich ELISA
特异性
Quantitative determination of Human ST2/IL-1 RL1
线性范围
7.8-500 pg/mL
ELISA 抗体对套装（非即用型）组分
1. Capture Antibody 1 mg/mL of mouse anti-Human IL1RL1 / DER4 monoclonal antibody (in PBS, pH 7.4). Dilute to a working concentration of 2 μg/mL in PBS before coating. (Catalog: # 10105-MM10)
2. Detection Antibody 0.2 mg/mL of mouse anti-Human IL1RL1 / DER4 monoclonal antibody conjugated to horseradish-peroxidase (HRP) (in PBS, 50 % HRP-Protector, pH 7.4, store at 4℃). Dilute to working concentration of 1.2 μg/mL in detection antibody dilution buffer before use. (Catalog: # 10105-MM12)
3. Standard Each vial contains 28 ng of recombinant Human IL1RL1 / DER4. Reconstitute with 1 mL detection antibody dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in sample dilution buffer, and a high standard of 500 pg/mL is recommended.
2. Detection Antibody 0.2 mg/mL of mouse anti-Human IL1RL1 / DER4 monoclonal antibody conjugated to horseradish-peroxidase (HRP) (in PBS, 50 % HRP-Protector, pH 7.4, store at 4℃). Dilute to working concentration of 1.2 μg/mL in detection antibody dilution buffer before use. (Catalog: # 10105-MM12)
3. Standard Each vial contains 28 ng of recombinant Human IL1RL1 / DER4. Reconstitute with 1 mL detection antibody dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in sample dilution buffer, and a high standard of 500 pg/mL is recommended.
产品概述
This ST2/IL-1 RL1 Matched ELISA Antibody Pair Set,Human is a solid phase sandwich ELISA for quantitative determination of Human ST2/IL-1 RL1 . It contains Human ST2/IL-1 RL1 capture antibody, Human ST2/IL-1 RL1 detector antibody
(HRP)
and a highly purified
HEK293-expressed
recombinant Human ST2/IL-1 RL1 protein. This Pair Set is at affordable price for researchers.
运输方式
This Matched ELISA Antibody Pair Set is shipped at ambient temperature.
储存条件
Capture Antibody: Aliquot and store at -20℃ to -80℃ for up to 6 months from date of receipt. Avoid repeated freeze-thaw cycles.
Detection Antibody: Store at 4℃ and protect it from prolonged exposure to light for up to 6 months from date of receipt. DO NOT FREEZE!
Standard: Store lyophilized standard at -20℃ to -80℃ for up to 6 months from date of receipt. Aliquot and store the reconstituted Standard at -80℃ for up to 1 month. Avoid repeated freeze-thaw cycles.
Detection Antibody: Store at 4℃ and protect it from prolonged exposure to light for up to 6 months from date of receipt. DO NOT FREEZE!
Standard: Store lyophilized standard at -20℃ to -80℃ for up to 6 months from date of receipt. Aliquot and store the reconstituted Standard at -80℃ for up to 1 month. Avoid repeated freeze-thaw cycles.
ST2/IL-1 RL1 Matched ELISA Antibody Pair Set,Human 图片
ST2/IL-1 RL1 Matched ELISA Antibody Pair Set,Human: 别称
DER4 Matched ELISA Antibody Pair Set, Human; FIT-1 Matched ELISA Antibody Pair Set, Human; IL1RL1 Matched ELISA Antibody Pair Set, Human; IL33R Matched ELISA Antibody Pair Set, Human; IL‑1 R4 Matched ELISA Antibody Pair Set, Human; ST2 Matched ELISA Antibody Pair Set, Human; ST2L Matched ELISA Antibody Pair Set, Human; ST2V Matched ELISA Antibody Pair Set, Human; T1 Matched ELISA Antibody Pair Set, Human
ST2/IL-1 RL1 背景信息
IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagnose cardiovascular disease and determine the prognosis for a patient with cardiovascular disease. The ligand for IL1RL1 has been described and named IL-33. Mutants in IL1RL1 have been associated with blood eosinophil counts in a genome-wide association study and with asthma in family-based and case-control studies. As an important mediator involved in many immune and inflammatory responses, this cytokine has been implicated as a regulator of both the development and effector phases of type 2 helper T cell responses, and as a negative feedback modulator of macrophage proinflammatory function. IL33 is a specific ligand of ST2L and induces the production of Th2 cytokines.
全称
interleukin 1 receptor-like 1
Related Pathways
-
IL1 signaling pathway
参考文献
- Savenije OE, et al. (2011) Interleukin-1 receptor-like 1 polymorphisms are associated with serum IL1RL1-a, eosinophils, and asthma in childhood. J Allergy Clin Immunol. 127(3): 750-6.
- Li H, et al. (2000) The cloning and nucleotide sequence of human ST2L cDNA. Genomics. 67(3): 284-90.
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