TNFRSF1A Matched ELISA Antibody Pair Set,Human

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TNFRSF1A Matched ELISA Antibody Pair Set,Human 产品信息

产品名称
TNFRSF1A Matched ELISA Antibody Pair Set,Human
检测原理
Solid Phase Sandwich ELISA
特异性
Quantitative determination of Human TNFRSF1A
线性范围
7.81-500 pg/mL
ELISA 抗体对套装(非即用型)组分
1. Capture Antibody 0.5 mg/mL of mouse anti-TNFRI / CD120a monoclonal antibody. Dilute to a working concentration of 2.0 μg/mL in CBS before coating. (Catalog: # 10872-MM10)
2. Detection Antibody 0.5 mg/mL mouse anti-TNFRI / CD120a monoclonal antibody conjugated to horseradish-peroxidase (HRP). Dilute to a working concentration of 1.0 μg/mL in detection antibody dilution buffer before use. (Catalog: # 10872-MM09)
3. Standard Each vial contains 60 ng of recombinant anti-TNFRI / CD120a. Reconstitute with 1 mL detection antibody dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve usi ng 2-fold serial dilutions in sample dilution buffer, and a high standard of 500 pg/mL is recommended
产品概述
This TNFRSF1A Matched ELISA Antibody Pair Set,Human is a solid phase sandwich ELISA for quantitative determination of Human TNFRSF1A . It contains Human TNFRSF1A capture antibody, Human TNFRSF1A detector antibody (HRP) and a highly purified HEK293-expressed recombinant Human TNFRSF1A protein. This Pair Set is at affordable price for researchers.
运输方式
This Matched ELISA Antibody Pair Set is shipped at ambient temperature.
储存条件
Capture Antibody: Aliquot and store at -20℃ to -80℃ for up to 6 months from date of receipt. Avoid repeated freeze-thaw cycles.
Detection Antibody: Protect it from prolonged exposure to light. Aliquot and store at -20℃ to -80℃ and for up to 6 months from date of receipt. Avoid repeated freeze-thaw cycles.
Standard: Store lyophilized standard at -20℃ to -80℃ for up to 6 months from date of receipt. Aliquot and store the reconstituted Standard at -80℃ for up to 1 month. Avoid repeated freeze-thaw cycles.

TNFRSF1A Matched ELISA Antibody Pair Set,Human 图片

TNFRSF1A Matched ELISA Antibody Pair Set,Human: 别称

CD120a Matched ELISA Antibody Pair Set, Human; FPF Matched ELISA Antibody Pair Set, Human; MS5 Matched ELISA Antibody Pair Set, Human; p55 Matched ELISA Antibody Pair Set, Human; p55-R Matched ELISA Antibody Pair Set, Human; p60 Matched ELISA Antibody Pair Set, Human; TBP1 Matched ELISA Antibody Pair Set, Human; TNF-R Matched ELISA Antibody Pair Set, Human; TNF-R-I Matched ELISA Antibody Pair Set, Human; TNF-R55 Matched ELISA Antibody Pair Set, Human; TNFAR Matched ELISA Antibody Pair Set, Human; TNFR1 Matched ELISA Antibody Pair Set, Human; TNFR1-d2 Matched ELISA Antibody Pair Set, Human; TNFR55 Matched ELISA Antibody Pair Set, Human; TNFR60 Matched ELISA Antibody Pair Set, Human

TNFRSF1A 背景信息

The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD120a (cluste of differentiation 120a), also known as TNFR1 / TNFRSF1A, is a member of CD family, tumor necrosis factor receptor superfamily. CD120a is one of the most primary receptors for the tumor necrosis factor-alpha. It has been shown to be localized to both plasma membrane lipid rafts and the trans golgi complex with the help of the death domain (DD). CD120a can activate the transcription factor NF-κB, mediate apoptosis, and regulate inflammation processes.
全称
tumor necrosis factor receptor superfamily member 1A
研究领域
Related Pathways
  • Death Receptor Signaling
    Death Receptor Signaling
  • NF-kB (NFkB) Pathway
    NF-kB (NFkB) Pathway
  • TNF Signaling
    TNF Signaling
参考文献
  • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
  • Cottin V, et al. (2002) Restricted localization of the TNF receptor CD120a to lipid rafts: a novel role for the death domain. The journal of immunology. 168: 4095-102.
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