TROP2 Matched ELISA Antibody Pair Set,Human

For the orders from outside of China: MOQ 15 plates, lead time: 2 weeks.
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TROP2 Matched ELISA Antibody Pair Set,Human 产品信息

产品名称
TROP2 Matched ELISA Antibody Pair Set,Human
检测原理
Solid Phase Sandwich ELISA
特异性
Quantitative determination of Human TROP2
线性范围
31.25-2000 pg/mL
ELISA 抗体对套装(非即用型)组分
1. Capture Antibody 0.5 mg/mL of mouse anti-Human TROP-2 / TACSTD2 / TACD2 monoclonal antibody (in PBS, pH 7.4). Dilute to a working concentration of 2 μg/mL in PBS before coating. (Catalog: # 10428-MM02)
2. Detection Antibody 0.2 mg/mL of mouse anti-Human TROP-2 / TACSTD2 / TACD2 monoclonal antibody conjugated to horseradish-peroxidase (HRP) (in PBS, 50 % HRP-Protector, pH 7.4, store at 4℃). Dilute to working concentration of 0.5 μg/mL in detection antibody dilution buffer before use. (Catalog: # 10428-MM01)
3. Standard Each vial contains 90 ng of recombinant Human TROP-2 / TACSTD2 / TACD2. Reconstitute with 1 mL detection antibody dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in sample dilution buffer, and a high standard of 2000 pg/mL is recommended.
产品概述
This TROP2 Matched ELISA Antibody Pair Set,Human is a solid phase sandwich ELISA for quantitative determination of Human TROP2 . It contains Human TROP2 capture antibody, Human TROP2 detector antibody (HRP) and a highly purified HEK293-expressed recombinant Human TROP2 protein. This Pair Set is at affordable price for researchers.
运输方式
This Matched ELISA Antibody Pair Set is shipped at ambient temperature.
储存条件
Capture Antibody: Aliquot and store at -20℃ to -80℃ for up to 6 months from date of receipt. Avoid repeated freeze-thaw cycles.
Detection Antibody: Store at 4℃ and protect it from prolonged exposure to light for up to 6 months from date of receipt. DO NOT FREEZE!
Standard: Store lyophilized standard at -20℃ to -80℃ for up to 6 months from date of receipt. Aliquot and store the reconstituted Standard at -80℃ for up to 1 month. Avoid repeated freeze-thaw cycles.

TROP2 Matched ELISA Antibody Pair Set,Human 图片

TROP2 Matched ELISA Antibody Pair Set,Human: 别称

EGP-1 Matched ELISA Antibody Pair Set, Human; EGP1 Matched ELISA Antibody Pair Set, Human; GA733-1 Matched ELISA Antibody Pair Set, Human; GA7331 Matched ELISA Antibody Pair Set, Human; GP50 Matched ELISA Antibody Pair Set, Human; M1S1 Matched ELISA Antibody Pair Set, Human; TACD2 Matched ELISA Antibody Pair Set, Human; TROP-2 Matched ELISA Antibody Pair Set, Human; TROP2 Matched ELISA Antibody Pair Set, Human

TROP2 背景信息

TROP-2, also referred to as tumor-associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1, is a cell surface glycoprotein highly expressed in a wide variety of epithelial cancers. In contrast, there is little or no expression of Trop-2 in adult somatic tissue. Because it is a cell surface protein that is selectively expressed in tumor cells, Trop-2 is a potential therapeutic target. The cytoplasmic tail of Trop-2 possesses potential serine and tyrosine phosphorylation sites and a phosphatidyl-inositol binding consensus sequence. Trop-2 transduces an intracellular calcium signal, which are consistent with the hypothesis that it acts as a cell surface receptor and support a search for a physiological ligand. TROP2 encoding by an intronless gene was originally defined by the monoclonal antibody GA733, and is a member of a family of at least two type I membrane proteins. The other known member is GA733-2, also called EpCAM and TROP1. It has been suggested by studies that the GA733-1 gene was formed by the retroposition of the GA733-2 gene via an mRNA intermediate.
全称
tumor-associated calcium signal transducer 2
研究领域
参考文献
  • Ripani E, et al. (1998) Human Trop-2 is a tumor-associated calcium signal transducer. Int J Cancer. 76(5): 671-6.
  • Wang J, et al. (2008) Identification of Trop-2 as an oncogene and an attractive therapeutic target in colon cancers. Mol Cancer Ther. 7(2): 280-5.
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