PIK3CA (蛋白 | 抗体 | cDNA 克隆 | ELISA 试剂盒)

All PIK3CA reagents are produced in house and quality controlled, including 1 PIK3CA Antibody, 3 PIK3CA Gene. All PIK3CA reagents are ready to use.

PIK3CA 分子背景

Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 11 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. A pseudogene of this gene has been defined on chromosome 22.

PIK3CA 参考文献

  • Limaye N, Kangas J, Mendola A, et al. Somatic Activating PIK3CA Mutations Cause Venous Malformation. American Journal of Human Genetics. 2015;97(6):914-921.