Protein Gene Codon OPtimization Service Description

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Protein Gene Codon Optimization Service

Protein expression is a highly regulated process. Through millions of years of molecular evolution, the expression levels of different proteins are regulated throughout the protein expression process, such as transcription, translation, and post-translational modification. For various reasons, some proteins are down regulated to prevent harmful effects. For example, factor VIII plays critical role in bleeding coagulation, but too much of factor VIII in the blood can lead to stroke. Therefore, factor VIII expression level is very low. One of the approaches to down regulate factor VIII expression is the presence of many rare gene codons.

So protein gene codon optimization is necessary to artificially enhance low-expressing protein expression. It is also often used to improve expression of protein from a different species. Although widely practiced in life science community, protein gene codon optimization is not straightforward, and if not done correctly, it can cause poor protein expression.

Sino Biological has developed expertise and capability in house for automated protein gene codon optimization and has resulted in excellent results in thousands of protein and antibody expression. The technology has been fully validated.

How to Request for Protein Gene Codon Optimization Service?

If you are interested in using our codon optimization service, please contact us by leaving an on-line message, filling out an on-line inquiry form, or sending us your detailed requests to CRO-service@sinobiological.com. A formal quote will be send back to you for your review, comment, and/or acceptance.

Biology CRO Service
Biology CRO Service Introduction
Antibody Production & Development CRO Service
Protein Production CRO Service
Transient Transfection Service: Mammalian Cell Culture
Molecular Biology CRO Service
Gene Synthesis CRO Service+
- Monoclonal Antibody Gene Synthesis Service
- Protein Codon Optimization Service
Protein Gene Codon OPtimization Service Description
- Protein Gene Synthesis Service
- Gene Mutagenesis Service