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题目 PMID 年份 作者 期刊 分子 货号
Over-expression of Follistatin-like 3 attenuates fat accumulation and improves insulin sensitivity in mice 25456456 2014 C Brandt, RH Hansen, JB Hansen, CH Olsen, P Galle… Metabolism FSTL3 50029-M08H
Pan-amyloid oligomer specific scFv antibody attenuates memory deficits and brain amyloid burden in mice with Alzheimer's disease 24156260 2014 Zhao, M;Wang, SW;Wang, YJ;Zhang, R;Li, YN;Su, YJ;Zhou, WW;Yu, XL;Liu, RT; Curr Alzheimer Res HSPB2 10351-H08E
Pan-amyloid oligomer specific scFv antibody attenuates memory deficits and brain amyloid burden in mice with Alzheimer's disease 24156260 2014 Zhao, M;Wang, SW;Wang, YJ;Zhang, R;Li, YN;Su, YJ;Zhou, WW;Yu, XL;Liu, RT; Curr Alzheimer Res Hsp90 alpha 11445-HNCE
PD-L1 Expression Is Increased in a Subset of Basal Type Breast Cancer Cells 24551119 2014 Soliman, H;Khalil, F;Antonia, S; PLoS ONE PD-L1 10084-R015
PELP1 oncogenic functions involve alternative splicing via PRMT6 24447537 2014 Mann, M;Zou, Y;Chen, Y;Brann, D;Vadlamudi, R; Mol Oncol PRMT6 11313-H18H
Peptide-based isolation of circulating tumor cells by magnetic nanoparticles 2014 Bai, L;Du, Y;Peng, J;Liu, Y;Wang, Y;Yang, Y; Journal of Materials Chemistry B CD45 10086-MM05-F
Phage display as a tool for development of novel therapeutics for breast cancer 2014 Cabral, MJCD; Thesis Her2 / ERBB2 10004-H02H
Phage display as a tool for development of novel therapeutics for breast cancer 2014 Cabral, MJCD; Thesis Her2 / ERBB2 90020-MM01
Phage display as a tool for development of novel therapeutics for breast cancer 2014 Cabral, MJCD; Thesis DLL1 11635-MM07
PPARγ Recruitment to Active ERK during Memory Consolidation Is Required for Alzheimer's Disease-Related Cognitive Enhancement 24623782 2014 JB Jahrling, CM Hernandez, L Denner… The Journal of neuroscience ERK2 10030-H09B
Preparation and Evaluation of a CD13/APN-Targeting and Hydrolase-Resistant Conjugate that Comprises Pingyangmycin and NGR Motif-Integrated Apoprotein 24504597 2014 Li, B;Zheng, YB;Li, DD;Zhen, YS; J Pharm Sci BLMH 11333-H07E
Preparation and Evaluation of a CD13/APN-Targeting and Hydrolase-Resistant Conjugate that Comprises Pingyangmycin and NGR Motif-Integrated Apoprotein 24504597 2014 Li, B;Zheng, YB;Li, DD;Zhen, YS; J Pharm Sci BMP-2 10426-HNAE
Preparation and Evaluation of a CD13/APN-Targeting and Hydrolase-Resistant Conjugate that Comprises Pingyangmycin and NGR Motif-Integrated Apoprotein 24504597 2014 Li, B;Zheng, YB;Li, DD;Zhen, YS; J Pharm Sci BMP2 SEK10426
Preparation and properties of a papillomavirus infectious intermediate and its utility for neutralization studies 24418565 2014 Wang, JW;Jagu, S;Kwak, K;Wang, C;Peng, S;Kirnbauer, R;Roden, RB; Virology Furin HG10141-M
Prodrug-Inspired Probes Selective to Cathepsin B over Other Cysteine Cathepsins 24940640 2014 Chowdhury, MA;Moya, IA;Bhilocha, S;McMillan, CC;Vigliarolo, BG;Zehbe, I;Phenix, CP; J. Med. Chem. Cystatin B 10483-H08H
Prostatic acid phosphatase, compositions comprising the same, and methods for producing and/or purifying the same 2014 J Mitschelen, J Lightholder, G Bream… US Patent … Prostatic Acid Phosphatase 10959-H08H
Protective immunity to H7N9 influenza viruses elicited by synthetic DNA vaccine 24631084 2014 Yan, J;Villarreal, DO;Racine, T;Chu, JS;Walters, JN;Morrow, MP;Khan, AS;Sardesai, NY;Kim, JJ;Kobinger, GP;Weiner, DB; Vaccine Hemagglutinin / HA 11082-MM04
Rapid detection of 6×-histidine-labeled recombinant proteins by immunochromatography using dye-labeled cellulose nanobeads 25388454 2014 Choi, ES;Lee, SG;Lee, SJ;Kim, E; Biotechnol. Lett. GABARAPL1 14549-H07E
Recombinant IFN-α2a-NGR exhibits higher inhibitory function on tumor neovessels formation compared with IFN-α2a in vivo and in vitro 24897998 2014 W Li, Q Hao, L He, J Meng, M Li, X Xue, C Zhang, H Li… Cytotechnology CD13 10051-H08H
Reduced IL-35 levels are associated with increased platelet aggregation and activation in patients with acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation 25512184 2014 Zhang, X;Zhou, Y;Xu, L;Han, W;Chen, H;Chen, Y;Fu, H;Zhou, S;Zhao, J;Wang, Q;Feng, F;Zhu, X;Liu, K;Huang, X; Ann. Hematol. IL-35 (IL12A & EBI3 Heterodimer) 10705-H02H
Reformatting of scFv Antibodies into the scFv-Fc Format and Their Downstream Purification 24515475 2014 E Bujak, M Matasci, D Neri, S Wulhfard Methods in Molecular Biology Protein A 10600-P07E-RN
Repurposing of clinically developed drugs for treatment of Middle East Respiratory Coronavirus Infection 24841273 2014 Dyall, J;Coleman, CM;Hart, BJ;Venkataraman, T;Holbrook, MR;Kindrachuk, J;Johnson, RF;Olinger, GG;Jahrling, PB;Laidlaw, M;Johansen, LM;Lear, CM;Glass, PJ;Hensley, LE;Frieman, MB; Antimicrob. Agents Chemother. CoV spike 40069-RP02
Retinol binding protein 4 promotes hyperinsulinism‑induced proliferation of rat aortic smooth muscle cells 24604418 2014 Li, F;Xia, K;Sheikh, MS;Cheng, J;Li, C;Yang, T; Mol Med Rep RBP4 10354-H08H
Safety and tolerability of MRI-guided infusion of AAV2-hAADC into the mid-brain of nonhuman primate 25541617 2014 San Sebastian, W;Kells, AP;Bringas, J; MOLECULAR THERAPY — METHODS & CLINICAL DEVELOPMENT DDC SEK10560
Salivary biomarkers indicate obstructive sleep apnea patients with cardiovascular diseases 25395095 2014 Zheng, H;Li, R;Zhang, J;Zhou, S;Ma, Q;Zhou, Y;Chen, F;Lin, J; Sci Rep Fetuin B 10318-R001
Signal on fluorescence biosensor for MMP-2 based on FRET between semiconducting polymer dots and a metal organic framework 2014 Yang, W;Zhang, G;Weng, W;Qiu, B;Guo, L;Lin, Z; RSC Advances MMP1 10532-H08H
SOCS3 methylation in synergy with Reg3A overexpression promotes cell growth in pancreatic cancer 24996521 2014 Wang, J;Zhou, H;Han, Y;Liu, X;Wang, M;Wang, X;Yin, G;Li, X;Xiang, M; J. Mol. Med. Reg3A 11235-H08H
Soluble production of a biologically active single-chain antibody against murine PD-L1 in Escherichia coli 24215864 2014 JJ Drees, LB Augustin, MJ Mertensotto… Protein Expression and Purification PD-L1 50010-M08H
Specific Contactin N-glycans are implicated in Neurofascin binding and autoimmune targeting in peripheral neuropathies 24497634 2014 Labasque, M;Hivert, B;Nogales-Gadea, G;Querol, L;Illa, I;Faivre-Sarrailh, C; J. Biol. Chem. Contactin-1 10383-H08H
Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage 24407422 2014 Zhao, L;Hua, T;Crowley, C;Ru, H;Ni, X;Shaw, N;Jiao, L;Ding, W;Qu, L;Hung, LW;Huang, W;Liu, L;Ye, K;Ouyang, S;Cheng, G;Liu, ZJ; Cell Res. PAEP 50051-M07H
Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage 24407422 2014 Zhao, L;Hua, T;Crowley, C;Ru, H;Ni, X;Shaw, N;Jiao, L;Ding, W;Qu, L;Hung, LW;Huang, W;Liu, L;Ye, K;Ouyang, S;Cheng, G;Liu, ZJ; Cell Res. PAEP 62001-W08H
Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage 24407422 2014 Zhao, L;Hua, T;Crowley, C;Ru, H;Ni, X;Shaw, N;Jiao, L;Ding, W;Qu, L;Hung, LW;Huang, W;Liu, L;Ye, K;Ouyang, S;Cheng, G;Liu, ZJ; Cell Res. Cystatin C 10439-H08H
Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage 24407422 2014 Zhao, L;Hua, T;Crowley, C;Ru, H;Ni, X;Shaw, N;Jiao, L;Ding, W;Qu, L;Hung, LW;Huang, W;Liu, L;Ye, K;Ouyang, S;Cheng, G;Liu, ZJ; Cell Res. Cystatin B 50084-M08H
Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage 24407422 2014 Zhao, L;Hua, T;Crowley, C;Ru, H;Ni, X;Shaw, N;Jiao, L;Ding, W;Qu, L;Hung, LW;Huang, W;Liu, L;Ye, K;Ouyang, S;Cheng, G;Liu, ZJ; Cell Res. Cathepsin S 50769-M08H
Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage 24407422 2014 Zhao, L;Hua, T;Crowley, C;Ru, H;Ni, X;Shaw, N;Jiao, L;Ding, W;Qu, L;Hung, LW;Huang, W;Liu, L;Ye, K;Ouyang, S;Cheng, G;Liu, ZJ; Cell Res. Cathepsin L 50015-M08H
STUB1 mutations in autosomal recessive ataxias–evidence for mutation-specific clinical heterogeneity 25258038 2014 K Heimdal, M Sanchez-Guixé, I Aukrust… Orphanet Journal of Rare Diseases HSC70 11329-H07E
Sublytic C5b-9 induces IL-6 and TGF-β1 production by glomerular mesangial cells in rat Thy-1 nephritis through p300-mediated C/EBPβ acetylation 24344329 2014 Zhang, J;Li, Y;Shan, K;Wang, L;Qiu, W;Lu, Y;Zhao, D;Zhu, G;He, F;Wang, Y; FASEB J. C6 12426-H08H
Synthesis and anti-influenza virus activity of 4-oxo- or thioxo-4,5-dihydrofuro[3,4-c]pyridin-3(1H)-ones 24794525 2014 Jang, YJ;Achary, R;Lee, HW;Lee, HJ;Lee, CK;Han, SB;Jung, YS;Kang, NS;Kim, P;Kim, M; Antiviral Res. Hemagglutinin / HA 86001-RM01
Synthesis and anti-influenza virus activity of 4-oxo- or thioxo-4,5-dihydrofuro[3,4-c]pyridin-3(1H)-ones 24794525 2014 Jang, YJ;Achary, R;Lee, HW;Lee, HJ;Lee, CK;Han, SB;Jung, YS;Kang, NS;Kim, P;Kim, M; Antiviral Res. Nucleocapsid / NP 11675-MM03
Synthetic di-sulfated iduronic acid attenuates asthmatic response by blocking T-cell recruitment to inflammatory sites 24835176 2014 M Nonaka, X Bao, F Matsumura… CrossMark CCL21 10477-HNAB
Targeted Activation of Human Vγ9Vδ2-T Cells Controls Epstein-Barr Virus-Induced B Cell Lymphoproliferative Disease 25220446 2014 Z Xiang, Y Liu, J Zheng, M Liu, A Lv, Y Gao, H Hu… Cancer cell MICA 12302-H08H
Technical Advance: Ascorbic acid induces development of double-positive T cells from human hematopoietic stem cells in the absence of stromal cells 25157026 2014 Huijskens, MJ;Walczak, M;Koller, N;Briedé, JJ;Senden-Gijsbers, BL;Schnijderberg, MC;Bos, GM;Germeraad, WT; J. Leukoc. Biol. DLL4 10171-H02H
The importance of pyroglutamate in cellulase Cel7A 24375151 2014 Dana, CM;Dotson-Fagerstrom, A;Roche, CM;Kal, SM;Chokhawala, HA;Blanch, HW;Clark, DS; Biotechnol. Bioeng. QPCT 13752-H07B
The nuclear bile acid receptor FXR controls the liver derived tumor suppressor histidine-rich glycoprotein 25363753 2014 Deuschle, U;Birkel, M;Hambruch, E;Hornberger, M;Kinzel, O;Perović-Ottstadt, S;Schulz, A;Hahn, U;Burnet, M;Kremoser, C; Int. J. Cancer HRG SEK10836
The production of coagulation factor VII by adipocytes is enhanced by tumor necrosis factor-α or isoproterenol 2014 Takahashi, N;Yoshizaki, T;Hiranaka, N;Kumano, O;Suzuki, T;Akanuma, M;Yui, T;Kanazawa, K;Yoshida, M;Naito, S;Fujiya, M;Kohgo, Y;Ieko, M; Int J Obes (Lond) Factor VII SEK50034
The receptors CD96 and CD226 oppose each other in the regulation of natural killer cell functions 24658051 2014 CJ Chan, L Martinet, S Gilfillan… Nature immunology CD155 / PVR 10109-H02H
Three-dimensional structure of human γ-secretase 2014 Peilong Lu #1,3 , Xiao-chen Bai #4 , Dan Ma #1,3 , Tian Xie 1,3 , Chuangye Yan 2,3 , Linfeng Sun 1,3 , Guanghui Yang 2,3 , Yanyu Zhao 1,3 , Rui Zhou 1,3 , Sjors H.W. Scheres 4 , and Yigong Shi 1,3 Nature medium SMM 293T-I
TLR Signals Induce Phagosomal MHC-I Delivery from the Endosomal Recycling Compartment to Allow Cross-Presentation 25083866 2014 Nair-Gupta, P;Baccarini, A;Tung, N;Seyffer, F;Florey, O;Huang, Y;Banerjee, M;Overholtzer, M;Roche, PA;Tampé, R;Brown, BD;Amsen, D;Whiteheart, SW;Blander, JM; Cell Hemagglutinin / HA 40196-VNAHC
TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis 24990881 2014 G Kleinberger, Y Yamanishi… Science Translational Medicine TREM-2 SEK11084
Trichomide A, a Natural Cyclodepsipeptide, Exerts Immunosuppressive Activity against Activated T Lymphocytes by Upregulating SHP2 Activation to Overcome Contact Dermatitis 24933319 2014 Wang, X;Zhang, A;Gao, J;Chen, W;Wang, S;Wu, X;Shen, Y;Ke, Y;Hua, Z;Tan, R;Sun, Y;Xu, Q; J. Invest. Dermatol. SHP2 50462-M08H
Ubiquitination of inositol-requiring enzyme 1 (IRE1) by the E3 ligase CHIP mediates the IRE1/TRAF2/JNK pathway 25225294 2014 X Zhu, J Zhang, H Sun, C Jiang, Y Dong, Q Shan… JOURNAL OF BIOLOGICAL CHEMISTRY IRE1 11905-H20B
Upregulation of chemokine receptor CCR10 is essential for glioma proliferation, invasion and patient survival 25149529 2014 Chen, L;Liu, X;Zhang, HY;Du, W;Qin, Z;Yao, Y;Mao, Y;Zhou, L; Oncotarget CCL27 10625-H07E
Virus-like nanoparticle and DNA vaccination confers protection against respiratory syncytial virus by modulating innate and adaptive immune cells 25109662 2014 Ko, EJ;Kwon, YM;Lee, JS;Hwang, HS;Yoo, SE;Lee, YN;Lee, YT;Kim, MC;Cho, MK;Lee, YR;Quan, FS;Song, JM;Lee, S;Moore, ML;Kang, SM; Nanomedicine RSV Glycoprotein G 11070-V08H2
Vγ2Vδ2 T cell Costimulation Increases NK cell Killing of Monocyte‐derived Dendritic Cells 25227493 2014 C Cairo, N Surendran, KM Harris… Immunology ICOS 11559-H02H
Δ(9)-Tetrahydrocannabinol Treatment During Human Monocyte Differentiation Reduces Macrophage Susceptibility to HIV-1 Infection 24562630 2014 Williams, JC;Appelberg, S;Goldberger, BA;Klein, TW;Sleasman, JW;Goodenow, MM; J Neuroimmune Pharmacol HIV Gag-p24 SEK11695
A graphene oxide-based FRET sensor for rapid and sensitive detection of matrix metalloproteinase 2 in human serum sample 23623988 2013 Song, E;Cheng, D;Song, Y;Jiang, M;Yu, J;Wang, Y; Biosens Bioelectron MMP-2 10082-HNAH
A highly potent and specific MET therapeutic protein antagonist with both ligand-dependent and ligand-independent activity 24002935 2013 SA Olwill, C Joffroy, H Gille, E Vigna… Molecular Cancer Therapeutics TrkA 11073-H08H
A laboratory evaluation of medicinal herbs used in china for the treatment of hand, foot, and mouth disease 23554831 2013 Chen, X;Wang, C;Xu, L;Chen, X;Wang, W;Yang, G;Tan, RX;Li, E;Jin, Y; Evid Based Complement Alternat Med TNF-alpha 10602-HNAE
A novel DNA vaccine expressing the Ag85A-HA2 fusion protein provides protection against influenza A virus and Staphylococcus aureus 23369570 2013 Dai, J;Pei, D;Wang, B;Kuang, Y;Ren, L;Cao, K;Zuo, B;Shao, J;Li, S;Jiang, Z;Li, H;Li, M; Virol. J. Hemagglutinin / HA 11684-V08H
A novel DNA vaccine expressing the Ag85A-HA2 fusion protein provides protection against influenza A virus and Staphylococcus aureus 23369570 2013 Dai, J;Pei, D;Wang, B;Kuang, Y;Ren, L;Cao, K;Zuo, B;Shao, J;Li, S;Jiang, Z;Li, H;Li, M; Virol. J. HA 11055-RP02
A surface plasmon resonance assay to determine the effect of influenza neuraminidase mutations on its affinity with antiviral drugs 2013 Somasundaram, B; Thesis Neuraminidase / NA 11058-MM07
ADAM17 mediates hypoxia-induced drug resistance in hepatocellular carcinoma cells through activation of EGFR/PI3K/Akt pathway 23625205 2013 Wang, XJ;Feng, CW;Li, M; Mol. Cell. Biochem. HIF-1 alpha HG11977-G
Antibody Specific for CD22 and Methods of Use Thereof 2013 D Rabuka, RGE Holgate, FJ Carr US 20140161870 A1 CD22 11958-H08H
Anti-serpin antibody-mediated regulation of proteases in autoimmune diabetes 23195956 2013 Baldzizhar, R;Fedorchuk, C;Jha, M;Rathinam, C;Henegariu, O;Czyzyk, J; J. Biol. Chem. CD4 50134-M08H
Antiviral activity of carnosic acid against respiratory syncytial virus 24103432 2013 Shin, HB;Choi, MS;Ryu, B;Lee, NR;Kim, HI;Choi, HE;Chang, J;Lee, KT;Jang, DS;Inn, KS; Virol. J. RSV Fusion 11049-R009
Apolipoproteins C-I and C-III inhibit lipoprotein lipase activity by displacement of the enzyme from lipid droplets 24121499 2013 Larsson, M;Vorrsjö, E;Talmud, P;Lookene, A;Olivecrona, G; J. Biol. Chem. Apolipoprotein A-I 10686-H07E
Binding members to il-1 beta 2013 S Grabulovski, T Kretzschmar, S Schmitt… US 20140134183 A1 IL-1 beta 90010-CNAE
Bispecific igg antibodies as t cell engagers 2013 ABH Bakker, PF Van Loo… US 20140120096 A1 CLEC12A 11896-H07H