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题目 PMID 年份 作者 期刊 分子 货号
Enterokinase monolithic bioreactor as an efficient tool for biopharmaceuticals preparation: on-line cleavage of fusion proteins and analytical characterization of released products 29754038 2018 Tengattini, S;Rinaldi, F;Piubelli, L;Kupfer, T;Peters, B;Bavaro, T;Calleri, E;Massolini, G;Temporini, C; J Pharm Biomed Anal Enterokinase 10002-B08Y
EMAPII Monoclonal Antibody Ameliorates Influenza A Virus-Induced Lung Injury 29910176 2018 Lu, H;Chelvanambi, S;Poirier, C;Saliba, J;March, KL;Clauss, M;Bogatcheva, NV; Mol. Ther. EMAP-II HP100603
EP300-Mediated Lysine 2-Hydroxyisobutyrylation Regulates Glycolysis 29775581 2018 Huang, H;Tang, S;Ji, M;Tang, Z;Shimada, M;Liu, X;Qi, S;Locasale, JW;Roeder, RG;Zhao, Y;Li, X; Mol. Cell ENO1 HG11554-NY
Hydroxamic Acids Constitute a Novel Class of Autotaxin Inhibitors that Exhibit in Vivo Efficacy in a Pulmonary Fibrosis Model 29620892 2018 Nikolaou, A;Ninou, I;Kokotou, MG;Kaffe, E;Afantitis, A;Aidinis, V;Kokotos, G; J. Med. Chem. ENPP2 50663-M07H
Assembling and decorating hyaluronan hydrogels with twin protein superglues to mimic cell-cell interactions 30053659 2018 Wieduwild, R;Howarth, M; Biomaterials EpCAM HG10694-G
EphrinB/EphB signaling contributes to spinal nociceptive processing via calpain‑1 and caspase‑3 29749521 2018 Yang, M;Chen, W;Zhang, Y;Yang, R;Wang, Y;Yuan, H; Mol Med Rep EphB2 51367‑M02H
Juxtacrine signaling inhibits antitumor immunity by upregulating PD-L1 expression 29789418 2018 Yang, WH;Cha, JH;Xia, W;Lee, HH;Chan, LC;Wang, YN;Hsu, JL;Ren, G;Hung, MC; Cancer Res. Ephrin A3 10188-H08H
Efficient production of Trastuzumab Fab antibody fragments in Brevibacillus choshinensis expression system 29857036 2018 Mizukami, M;Onishi, H;Hanagata, H;Miyauchi, A;Ito, Y;Tokunaga, H;Ishibashi, M;Arakawa, T;Tokunaga, M; Protein Expr. Purif. Her2 / ERBB2 10004-H02H
Harnessing iNKT and CD8 T cells for Immunotherapy of Cancer 2018 Tschumi, BO; Thesis Her2 / ERBB2 10004-H02H
High affinity single-chain variable fragments are specific and versatile targeting motifs for extracellular vesicles 30010165 2018 Longatti, A;Schindler, C;Collinson, A;Jenkinson, L;Matthews, C;Fitzpatrick, L;Blundy, M;Minter, R;Vaughan, T;Shaw, M;Tigue, N; Nanoscale Her2 / ERBB2 10004-H02H
Single-step Enzymatic Glycoengineering for the Construction of Antibody-cell Conjugates 2018 Li, J;Chen, M;Liu, Z;Zhang, L;Felding, B;Lauvau, G;Abadier, M;Ley, K;Wu, P; bioRxiv Her2 / ERBB2 10004-H08H
Site-Specific Photoconjugation of Beta-Lactamase Fragments to Monoclonal Antibodies Enables Sensitive Analyte Detection via Split-Enzyme Complementation 29485240 2018 Yu, F;Alesand, V;Nygren, PÅ; Biotechnol J Her2 / ERBB2 10004-H08H
Structural and functional characterization of MBS301, an afucosylated bispecific anti-HER2 antibody 30081724 2018 Huang, S;Li, F;Liu, H;Ye, P;Fan, X;Yuan, X;Wu, Z;Chen, J;Jin, C;Shen, B;Feng, J;Zhang, B; MAbs Her2 / ERBB2 10004-H08H
Site-Specific Photoconjugation of Beta-Lactamase Fragments to Monoclonal Antibodies Enables Sensitive Analyte Detection via Split-Enzyme Complementation 29485240 2018 Yu, F;Alesand, V;Nygren, PÅ; Biotechnol J HER3 / ERBB3 10201-H08H
Specific glycosaminoglycan chain length and sulfation patterns are required for cell uptake of tau vs. α-synuclein and β-amyloid aggregates 2018 Stopschinski, BE;Holmes, BB;Miller, GM;Manon, VA;Vaquer-Alicea, J;Prueitt, WL;Hsieh-Wilson, LC;Diamond, MI; J. Biol. Chem. EXT1 HG14304-CY
Nitazoxanide inhibits paramyxovirus replication by targeting the Fusion protein folding: role of glycoprotein-specific thiol oxidoreductase ERp57 29992955 2018 Piacentini, S;La Frazia, S;Riccio, A;Pedersen, JZ;Topai, A;Nicolotti, O;Rossignol, JF;Santoro, MG; Sci Rep RSV Fusion VG40042-CF
Immunogenic Determinants of Coagulation Factor VIII 21649795 2018 Winterling, K; Thesis Factor VIII 13909-R226
Lentiviral delivery of novel fusion protein IL12/FasTI for cancer immune/gene therapy 30044833 2018 Yang, X;Yu, X;Wei, Y; PLoS ONE Fas MG50027-CH
Fingolimod inhibits brain atrophy and promotes brain-derived neurotrophic factor in an animal model of multiple sclerosis 29530550 2018 Smith, PA;Schmid, C;Zurbruegg, S;Jivkov, M;Doelemeyer, A;Theil, D;Dubost, V;Beckmann, N; J. Neuroimmunol. FCGR4 50036-RP02
Androgen Promotes Differentiation of PLZF+ Spermatogonia pool via Indirect Regulatory Pattern 2018 Wang, J;Li, J;Gu, Y;Xia, Q;Song, W;Zhang, X;Yang, Y;Wang, W;Li, H;Zou, K; bioRxiv FGF2 10014-HNAE
Exostosin-like 2 regulates FGF2 signaling by controlling the endocytosis of FGF2 29305908 2018 Nadanaka, S;Kitagawa, H; Biochim. Biophys. Acta FGF2 50037-M07E
In Vitro Modeling of Human Germ Cell Development Using Pluripotent Stem Cells 29398481 2018 Zhao, Y;Ye, S;Liang, D;Wang, P;Fu, J;Ma, Q;Kong, R;Shi, L;Gong, X;Chen, W;Ding, W;Yang, W;Zhu, Z;Chen, H;Sun, X;Zhu, J;Li, Z;Wang, Y; Stem Cell Reports FGF2 10014-HNAE
A2A Receptor Activation Attenuates Hypertensive Cardiac Remodeling via Promoting Brown Adipose Tissue-Derived FGF21 30017353 2018 Ruan, CC;Kong, LR;Chen, XH;Ma, Y;Pan, XX;Zhang, ZB;Gao, PJ; Cell Metab. FGF21 10911-H07E
Bioactivation of Spider Silk with Basic Fibroblast Growth Factor for in Vitro Cell Culture: A Step toward Creation of Artificial ECM 2018 Thatikonda, N;Nilebäck, L;Kempe, A;Widhe, M;Hedhammar, M; ACS Biomater. Sci. Eng. FGFR2 10824-H03H
Fumarate hydratase-specific T cell response in Chinese patients with autoimmune hepatitis 29610041 2018 Zhao, Y;Li, Y;Zhao, D;Zhang, H;Liu, Y;Liao, H;Zhang, Y;Yan, H; Clin Res Hepatol Gastroenterol FH 12115-H08E
Surface plasmon resonance imaging validation of small molecule drugs binding on target protein microarrays 2018 Zhou, W;Yang, M;Li, S;Zhu, J; Applied Surface Science FKBP12 10268-H08E
Folate Receptor Alpha Peptide Vaccine generates immunity in Breast and Ovarian Cancer Patients 29545464 2018 Kalli, KR;Block, MS;Kasi, PM;Erskine, CL;Hobday, TJ;Dietz, A;Padley, D;Gustafson, MP;Shreeder, B;Puglisi-Knutson, D;Visscher, DW;Mangskau, TK;Wilson, G;Knutson, KL; Clin. Cancer Res. FOLR1 11241-H08H
Follistatin-like protein 1 sustains colon cancer cell growth and survival 30131854 2018 Bevivino, G;Sedda, S;Franzè, E;Stolfi, C;Di Grazia, A;Dinallo, V;Caprioli, F;Facciotti, F;Colantoni, A;Ortenzi, A;Rossi, P;Monteleone, G; Oncotarget FSTL1 10924-H08H
Comparison of exosomes and ferritin protein nanocages for the delivery of membrane protein therapeutics 29679665 2018 Cho, E;Nam, GH;Hong, Y;Kim, YK;Kim, DH;Yang, Y;Kim, IS; J Control Release Ferritin heavy chain 1 HG13217-G
Indirect ELISA based on Hendra and Nipah virus proteins for the detection of henipavirus specific antibodies in pigs Indirect ELISA based on Hendra and Nipah virus proteins for the detection of henipavirus specific antibodies in pigs 2018 Fischer, K;Diederich, S;Smith, G;Reiche, S;Pinho Dos Reis, V;Stroh, E;Groschup, MH;Weingartl, HM;Balkema-Buschmann, A; PLoS ONE HeV Glycoprotein 40335-V02H
Clptm1 Limits Forward Trafficking of GABA A Receptors to Scale Inhibitory Synaptic Strength 29395912 2018 Ge, Y;Kang, Y;Cassidy, R;Moon, K;Lewis, R;Wong, R;Foster, L;Craig, A; Neuron GABRA4 HG14855-NY
Clptm1 Limits Forward Trafficking of GABA A Receptors to Scale Inhibitory Synaptic Strength 29395912 2018 Ge, Y;Kang, Y;Cassidy, R;Moon, K;Lewis, R;Wong, R;Foster, L;Craig, A; Neuron GABRD HG14909-NY
DNA damage response induced by Etoposide promotes steroidogenesis via GADD45A in cultured adrenal cells 29941883 2018 Tamamori-Adachi, M;Koga, A;Susa, T;Fujii, H;Tsuchiya, M;Okinaga, H;Hisaki, H;Iizuka, M;Kitajima, S;Okazaki, T; Sci Rep GADD45A HG11156-CF
Impacts of CyhospitalclinE downstream vimentin on proliferation, invasion and apoptosis of hepatoma HepG2 cell 2018 Hu, G;Jia, F;Gao, N;Han, Y; International Journal of Clinical and Experimental Medicine GAPDH 100242-T40
Overexpression of mRNA‑decapping enzyme 1a affects survival rate in colorectal carcinoma 29963186 2018 Wu, C;Liu, W;Ruan, T;Zhu, X;Tao, K;Zhang, W; Oncol Lett GAPDH HP100003
Fine Mapping the Interaction Between Dendritic CellSpecific Intercellular Adhesion Molecule (ICAM)-3- Grabbing Nonintegrin and the Cytomegalovirus Envelope Glycoprotein B 29648611 2018 Cheneau, C;Coulon, F;Porkolab, V;Fieschi, F;Laurant, S; The Journal of Infectious Diseases CMV Glycoprotein B 10202-RP01
Fine-mapping the interaction between DC-SIGN and the cytomegalovirus envelope glycoprotein B 29648611 2018 Chéneau, C;Coulon, F;Porkolab, V;Fieschi, F;Laurant, S;Razanajaona-Doll, D;Pin, JJ;Borst, EM;Messerle, M;Bressollette-Bodin, C;Halary, F; J. Infect. Dis. CMV Glycoprotein B 10202-RP01
Androgen Promotes Differentiation of PLZF+ Spermatogonia pool via Indirect Regulatory Pattern 2018 Wang, J;Li, J;Gu, Y;Xia, Q;Song, W;Zhang, X;Yang, Y;Wang, W;Li, H;Zou, K; bioRxiv GDNF 10561-HNCH
In Vitro Modeling of Human Germ Cell Development Using Pluripotent Stem Cells 29398481 2018 Zhao, Y;Ye, S;Liang, D;Wang, P;Fu, J;Ma, Q;Kong, R;Shi, L;Gong, X;Chen, W;Ding, W;Yang, W;Zhu, Z;Chen, H;Sun, X;Zhu, J;Li, Z;Wang, Y; Stem Cell Reports GDNF 10561-HNCH
Antibody Epitope of human α-Galactosidase A revealed by affinity-mass spectrometry: A basis for reversing immunoreactivity in enzyme replacement therapy of Fabry's Disease 29473701 2018 Przybylski, M; ChemMedChem GLA 12078-H08H
Design of Fusion Proteins for Efficient and Soluble Production of Immunogenic Ebola Virus Glycoprotein in Escherichia coli 29500882 2018 Ji, Y;Lu, Y;Yan, Y;Liu, X;Su, N;Zhang, C;Bi, S;Xing, XH; Biotechnol J Ebola virus Glycoprotein 40442-V08B1
Design of Fusion Proteins for Efficient and Soluble Production of Immunogenic Ebola Virus Glycoprotein in Escherichia coli 29500882 2018 Ji, Y;Lu, Y;Yan, Y;Liu, X;Su, N;Zhang, C;Bi, S;Xing, XH; Biotechnol J Ebola virus Glycoprotein 40442-T48
Elevated GPC3 level promotes cell proliferation in liver cancer 29963171 2018 Wang, S;Chen, N;Chen, Y;Sun, L;Li, L;Liu, H; Oncol Lett Glypican 3 10088-H08H
Immunization with glypican-3 nanovaccine containing TLR7 agonist prevents the development of carcinogen-induced precancerous hepatic lesions to cancer in a murine model 30018715 2018 Chen, K;Wu, Z;Zang, M;Wang, C;Wang, Y;Wang, D;Ma, Y;Qu, C; Am J Transl Res Glypican 3 10088-H08H
Repression of GRIM19 expression potentiates cisplatin chemoresistance in advanced bladder cancer cells via disrupting ubiquitination-mediated Bcl-xL degradation 30032449 2018 Ni, F;Yan, CY;Zhou, S;Hui, PY;Du, YH;Zheng, L;Yu, J;Hu, XJ;Zhang, ZG; Cancer Chemother. Pharmacol. NDUFA13/GRIM 19 HG16974-NF
A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA 29991715 2018 Bangaru, S;Zhang, H;Gilchuk, IM;Voss, TG;Irving, RP;Gilchuk, P;Matta, P;Zhu, X;Lang, S;Nieusma, T;Richt, JA;Albrecht, RA;Vanderven, HA;Bombardi, R;Kent, SJ;Ward, AB;Wilson, IA;Crowe, JE; Nat Commun Hemagglutinin / HA 40149-V08B
Chiral MoS2 Quantum Dots: Dual-Mode Detection Approaches for Avian Influenza Viruses 2018 Ahmed, S;Neethirajan, S; Global Challenges Hemagglutinin / HA 11699-RP02
Chiral MoS2 Quantum Dots: Dual-Mode Detection Approaches for Avian Influenza Viruses 2018 Ahmed, S;Neethirajan, S; Global Challenges Hemagglutinin / HA 11434-RP02
Chiral MoS2 Quantum Dots: Dual-Mode Detection Approaches for Avian Influenza Viruses 2018 Ahmed, S;Neethirajan, S; Global Challenges Hemagglutinin / HA 40014-V08H1
Chiral MoS2 Quantum Dots: Dual-Mode Detection Approaches for Avian Influenza Viruses 2018 Ahmed, S;Neethirajan, S; Global Challenges Hemagglutinin / HA 40172-V08H1
Chiral MoS2 Quantum Dots: Dual-Mode Detection Approaches for Avian Influenza Viruses 2018 Ahmed, S;Neethirajan, S; Global Challenges Hemagglutinin / HA 40104-V08H1
Double-layered protein nanoparticles induce broad protection against divergent influenza A viruses 29367723 2018 Deng, L;Mohan, T;Chang, TZ;Gonzalez, GX;Wang, Y;Kwon, YM;Kang, SM;Compans, RW;Champion, JA;Wang, BZ; Nat Commun Hemagglutinin / HA VG11088-UT
Double-layered protein nanoparticles induce broad protection against divergent influenza A viruses 29367723 2018 Deng, L;Mohan, T;Chang, TZ;Gonzalez, GX;Wang, Y;Kwon, YM;Kang, SM;Compans, RW;Champion, JA;Wang, BZ; Nat Commun Hemagglutinin / HA VG40351-UT
Double-layered protein nanoparticles induce broad protection against divergent influenza A viruses 29367723 2018 Deng, L;Mohan, T;Chang, TZ;Gonzalez, GX;Wang, Y;Kwon, YM;Kang, SM;Compans, RW;Champion, JA;Wang, BZ; Nat Commun Hemagglutinin / HA VG11684-UT
Double-layered protein nanoparticles induce broad protection against divergent influenza A viruses 29367723 2018 Deng, L;Mohan, T;Chang, TZ;Gonzalez, GX;Wang, Y;Kwon, YM;Kang, SM;Compans, RW;Champion, JA;Wang, BZ; Nat Commun Hemagglutinin / HA VG11707-UT
Dual-functional peptide with defective interfering genes effectively protects mice against avian and seasonal influenza 29907765 2018 Zhao, H;To, KKW;Chu, H;Ding, Q;Zhao, X;Li, C;Shuai, H;Yuan, S;Zhou, J;Kok, KH;Jiang, S;Yuen, KY; Nat Commun Hemagglutinin / HA 11055-V08H4
Dual-functional peptide with defective interfering genes effectively protects mice against avian and seasonal influenza 29907765 2018 Zhao, H;To, KKW;Chu, H;Ding, Q;Zhao, X;Li, C;Shuai, H;Yuan, S;Zhou, J;Kok, KH;Jiang, S;Yuen, KY; Nat Commun Hemagglutinin / HA 11055-RP02
Enterokinase Enhances Influenza A Virus Infection by Activating Trypsinogen in Human Cell Lines 29629340 2018 Hayashi, H;Kubo, Y;Izumida, M;Takahashi, E;Kido, H;Sato, K;Yamaya, M;Nishimura, H;Nakayama, K;Matsuyama, T; Front. Cell. Infect. Microbiol. Hemagglutinin / HA 11684-RP01
H3N2 influenza virus infection enhances Oncostatin M expression in human nasal epithelium 30142324 2018 Tian, T;Zi, X;Peng, Y;Wang, Z;Hong, H;Yan, Y;Guan, W;Tan, KS;Liu, J;Ong, HH;Kang, X;Yu, J;Ong, YK;Thong, KT;Shi, L;Ye, J;Wang, DY; Exp. Cell Res. Hemagglutinin / HA 11707-RP01
In Situ Pt Staining Method for Simple, Stable, and Sensitive Pressure-Based Bioassays 29582655 2018 Li, J;Liu, F;Zhu, Z;Liu, D;Chen, X;Song, Y;Zhou, L;Yang, C; ACS Appl Mater Interfaces Hemagglutinin / HA SEK002
Inactivation of influenza A virus via exposure to silver nanoparticle-decorated silica hybrid composites 30014367 2018 Park, S;Ko, YS;Lee, SJ;Lee, C;Woo, K;Ko, G; Environ Sci Pollut Res Int Hemagglutinin / HA SEK11056
Lectin Affinity Plasmapheresis for Middle East Respiratory Syndrome-Coronavirus and Marburg Virus Glycoprotein Elimination 29698959 2018 Koch, B;Schult-Dietrich, P;Büttner, S;Dilmaghani, B;Lohmann, D;Baer, PC;Dietrich, U;Geiger, H; Blood Purif. Hemagglutinin / HA TB100028
Magnetic Nanozyme-Linked Immunosorbent Assay for Ultrasensitive Influenza A Virus Detection 29595253 2018 Oh, S;Kim, J;Tran, VT;Lee, DK;Ahmed, SR;Hong, JC;Lee, J;Park, EY;Lee, J; ACS Appl Mater Interfaces Hemagglutinin / HA 11683-V08H
Native human monoclonal antibodies with potent cross-lineage neutralization of influenza B viruses 29507069 2018 Vigil, A;Estélles, A;Kauvar, LM;Johnson, SK;Tripp, RA;Wittekind, M; Antimicrob. Agents Chemother. Hemagglutinin / HA 11053-V08H
Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses 29739835 2018 Pardi, N;Hogan, MJ;Naradikian, MS;Parkhouse, K;Cain, DW;Jones, L;Moody, MA;Verkerke, HP;Myles, A;Willis, E;LaBranche, CC;Montefiori, DC;Lobby, JL;Saunders, KO;Liao, HX;Korber, BT;et al. J. Exp. Med. Hemagglutinin / HA 11684-V08H
Simultaneous Targeting of Multiple Hemagglutinins to APCs for Induction of Broad Immunity against Influenza 29427414 2018 Anderson, AM;Baranowska-Hustad, M;Braathen, R;Grodeland, G;Bogen, B; J. Immunol. Hemagglutinin / HA VG11689-C
Simultaneous Targeting of Multiple Hemagglutinins to APCs for Induction of Broad Immunity against Influenza 29427414 2018 Anderson, AM;Baranowska-Hustad, M;Braathen, R;Grodeland, G;Bogen, B; J. Immunol. Hemagglutinin / HA VG11723-C
Simultaneous Targeting of Multiple Hemagglutinins to APCs for Induction of Broad Immunity against Influenza 29427414 2018 Anderson, AM;Baranowska-Hustad, M;Braathen, R;Grodeland, G;Bogen, B; J. Immunol. Hemagglutinin / HA VG11722-C