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题目 PMID 年份 作者 期刊 分子 货号
S100A4 promotes lung tumor development through β-catenin pathway-mediated autophagy inhibition 29449540 2018 Hou, S;Tian, T;Qi, D;Sun, K;Yuan, Q;Wang, Z;Qin, Z;Wu, Z;Chen, Z;Zhang, J; Cell Death Dis S100A4 10185-H01H
Cyclin E2-CDK2 mediate SAMHD1 phosphorylation to abrogate its restriction of HBV replication in hepatoma cells 29782647 2018 Hu, J;Qiao, M;Chen, Y;Tang, H;Zhang, W;Tang, D;Pi, S;Dai, J;Tang, N;Huang, A;Hu, Y; FEBS Lett. SAMHD1 HG13780-NY
Mutations in VP1 and 5'-UTR affect enterovirus 71 virulence 29703921 2018 Chang, CK;Wu, SR;Chen, YC;Lee, KJ;Chung, NH;Lu, YJ;Yu, SL;Liu, CC;Chow, YH; Sci Rep SCARB2 11063-H03H
Dually Modified Transmembrane Proteoglycan TβRIII/Betaglycan in Cell Signaling and Cancer 2018 Jenkins, LM; Thesis Syndecan-1 MG50641-MF
Chrono-pharmacological Targeting of the CCL2-CCR2 Axis Ameliorates Atherosclerosis 29861387 2018 Winter, C;Silvestre-Roig, C;Ortega-Gomez, A;Lemnitzer, P;Poelman, H;Schumski, A;Winter, J;Drechsler, M;de Jong, R;Immler, R;Sperandio, M;Hristov, M;Zeller, T;Nicolaes, GAF;Weber, C;Viola, JR;Hidalgo, A;Scheiermann, C;Soehnlein, O; Cell Metab. E-Selectin 50736-MCCH
Microfluidics-based super-resolution microscopy enables nanoscopic characterization of blood stem cell rolling 30035228 2018 AbuZineh, K;Joudeh, LI;Al Alwan, B;Hamdan, SM;Merzaban, JS;Habuchi, S; Sci Adv E-Selectin 10335-H03H
Chrono-pharmacological Targeting of the CCL2-CCR2 Axis Ameliorates Atherosclerosis 29861387 2018 Winter, C;Silvestre-Roig, C;Ortega-Gomez, A;Lemnitzer, P;Poelman, H;Schumski, A;Winter, J;Drechsler, M;de Jong, R;Immler, R;Sperandio, M;Hristov, M;Zeller, T;Nicolaes, GAF;Weber, C;Viola, JR;Hidalgo, A;Scheiermann, C;Soehnlein, O; Cell Metab. P-Selectin 50737-M08H
Semaphorin3A induces nerve regeneration in the adult cornea-a switch from its repulsive role in development 29370308 2018 Zhang, M;Zhou, Q;Luo, Y;Nguyen, T;Rosenblatt, MI;Guaiquil, VH; PLoS ONE SEMA3A 50631-M01H
Semaphorin3A induces nerve regeneration in the adult cornea-a switch from its repulsive role in development 29370308 2018 Zhang, M;Zhou, Q;Luo, Y;Nguyen, T;Rosenblatt, MI;Guaiquil, VH; PLoS ONE SEMA3A 10758-H01H
Secreted Frizzled-Related Protein-2 Inhibits Doxorubicin Induced Apoptosis Mediated Through the Akt-mTOR Pathway in Soleus Muscle 30151071 2018 Merino, H;Singla, DK;Singla, DK; Thesis SFRP2 50028-M08H
SLAMF1 is required for TLR4-mediated TRAM-TRIF-dependent signaling in human macrophages SLAMF1 is required for TLR4-mediated TRAM-TRIF-dependent signaling in human macrophages 2018 Yurchenko, M;Skjesol, A;Ryan, L;Richard, GM;Kandasamy, RK;Wang, N;Terhorst, C;Husebye, H;Espevik, T; J. Cell Biol. SLAM / CD150 10837-R008
The Recombinant Human Secretory Leukocyte Protease Inhibitor (SLPI) protects cardiac fibroblasts injury against an in vitro ischemia/reperfusion injury 2018 Paiyabhroma, N;Nernpermpisooth, N; J App Pharm Sci SLPI 10343-H08B
Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability 29330478 2018 Williams, JJL;Alotaiq, N;Mullen, W;Burchmore, R;Liu, L;Baillie, GS;Schaper, F;Pilch, PF;Palmer, TM; Nat Commun SOCS3 11315-H30E
Revealing Synergistic Mechanism of Multiple Components in Gandi Capsule for Diabetic Nephropathy Therapeutics by Network Pharmacology 29853965 2018 Zhang, J;Zhang, Q;Chen, X;Liu, Y;Xue, J;Dahan, A;Zhang, H;Chai, Y; Evidence-Based Complementary and Alternative Medicine SOD1 11727-H07E
Interaction with SP1, but not binding to the E-box motifs, is responsible for BHLHE40/DEC1-induced transcriptional suppression of CLDN1 and cell invasion in MCF-7 cells 2018 Zheng, Q;Wang, C;Wang, L;Zhang, D;Liu, N;Ming, X;Zhou, H;Guli, Q;Liu, Y; Mol. Carcinog. SP1 HG12024-NM
Antibodies and methods for immunohistochemistry of extracellular matrix proteins 29730502 2018 Rickelt, S;Hynes, RO; Matrix Biol. SPARC 10929-RP02
Identification of a novel mutation (Ala66Thr) of SRY gene causes XY pure gonadal dysgenesis by affecting DNA binding activity and nuclear import 29378242 2018 Wang, X;Xue, M;Zhao, M;He, F;Li, C;Li, X; Gene SRY HG12062-NF
Influence of Th17/Treg balance on progression of liver cirrhosis in patients with chronic hepatitis B 22745730 2018 Wu, C;Dong, X;Yang, Q;Sun, Z; International Journal of Clinical and Experimental Medicine TGF beta 1 KIT10804
TIGIT-Fc alleviates acute graft-versus-host disease by suppressing CTL activation via promoting the generation of immunoregulatory dendritic cells 29960041 2018 Zhang, D;Hu, W;Xie, J;Zhang, Y;Zhou, B;Liu, X;Zhang, Y;Su, Y;Jin, B;Guo, S;Zhuang, R; Biochim. Biophys. Acta TIGIT MG50939-G
ADAM-17 is a poor prognostic indicator for patients with hilar cholangiocarcinoma and is regulated by FoxM1 29776401 2018 Jiao, X;Yu, W;Qian, J;Chen, Y;Wei, P;Fang, W;Yu, G; BMC Cancer TNF-alpha 10602-RP02
Inhibiting tumor necrosis factor-alpha at time of induced intervertebral disc injury limits long-term pain and degeneration in a rat model 29963655 2018 Evashwick-Rogler, T;Lai, A;Watanabe, H;Salandra, J;Winkelstein, B;Cho, S;Hecht, A;Iatridis, J; JOR Spine TNF-alpha 80045-RNAE
TGF-α Overexpression in Breast Cancer Bone Metastasis and Primary Lesions and TGF-α Enhancement of Expression of Procancer Metastasis Cytokines in Bone Marrow Mesenchymal Stem Cells 29581982 2018 Sun, J;Cui, H;Gao, Y;Pan, Y;Zhou, K;Huang, J;Lan, J;Wei, Q;Liu, X;Liu, L;Xian, C; BioMed Research International TNF-alpha 10602-HNAE
Targeting scFv-Fc-scTRAIL fusion proteins to tumor cells 29541416 2018 Hutt, M;Fellermeier-Kopf, S;Seifert, O;Schmitt, LC;Pfizenmaier, K;Kontermann, RE; Oncotarget DR5 50412-M03H
TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function 29518356 2018 Zhao, Y;Wu, X;Li, X;Jiang, LL;Gui, X;Liu, Y;Sun, Y;Zhu, B;Piña-Crespo, JC;Zhang, M;Zhang, N;Chen, X;Bu, G;An, Z;Huang, TY;Xu, H; Neuron TREM-1 10511-H08H
Cerebrospinal fluid soluble TREM2 levels in frontotemporal dementia differ by genetic and pathological subgroup 30111356 2018 Woollacott, IOC;Nicholas, JM;Heslegrave, A;Heller, C;Foiani, MS;Dick, KM;Russell, LL;Paterson, RW;Keshavan, A;Fox, NC;Warren, JD;Schott, JM;Zetterberg, H;Rohrer, JD; Alzheimers Res Ther TREM-2 11084-H08H
Cerebrospinal fluid tau, Aβ, and sTREM2 in Former National Football League Players: Modeling the relationship between repetitive head impacts, microglial activation, and neurodegeneration 30049650 2018 Alosco, ML;Tripodis, Y;Fritts, NG;Heslegrave, A;Baugh, CM;Conneely, S;Mariani, M;Martin, BM;Frank, S;Mez, J;Stein, TD;Cantu, RC;McKee, AC;Shaw, LM;Trojanowski, JQ;Blennow, K;Zetterberg, H;Stern, RA; Alzheimers Dement TREM-2 11084-H08H
Role of TREM-1 in pulmonary tuberculosis patients- analysis of serum soluble TREM-1 levels 29844416 2018 Feng, JY;Su, WJ;Pan, SW;Yeh, YC;Lin, YY;Chen, NJ; Sci Rep TREM-2 SEK11084
The MS4A gene cluster is a key regulator of soluble TREM2 and Alzheimer disease risk 29789534 2018 Deming, Y;Filipello, F;Cignarella, F;Hsu, S;Mikesell, R;Li, Z;Del-Aguila, J;Dube, U;Farias, F;Bradley, J;Cantoni, C;Benitez, B;Budde, J;Ibanez, L;Fernandez, M;et al. bioRxiv TREM-2 11084-H08H
TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function 29518356 2018 Zhao, Y;Wu, X;Li, X;Jiang, LL;Gui, X;Liu, Y;Sun, Y;Zhu, B;Piña-Crespo, JC;Zhang, M;Zhang, N;Chen, X;Bu, G;An, Z;Huang, TY;Xu, H; Neuron TREM-2 11084-H08H
ProBDNF/p75NTR/sortilin pathway is activated in peripheral blood of patients with alcohol dependence 29520063 2018 Zhou, L;Xiong, J;Ruan, CS;Ruan, Y;Liu, D;Bao, JJ;Zhou, XF; Transl Psychiatry TrkB SEK10047
VAMP-associated protein-A and oxysterol-binding protein-related protein 3 promote the entry of late endosomes into the nucleoplasmic reticulum 30018135 2018 Santos, MF;Rappa, G;Karbanova, J;Kurth, T;Corbeil, D;Lorico, A; J. Biol. Chem. VAPA HG11412-ACG
Identification of Functional mimotopes of human Vasorin Ectodomain by Biopanning 29725267 2018 Li, D;Zhang, T;Yang, X;Geng, J;Li, S;Ding, H;Li, H;Huang, A;Wang, C;Sun, L;Bai, C;Zhang, H;Li, J;Dong, J;Shao, N; Int. J. Biol. Sci. SLITL2 KIT13854
Reduced vasorin enhances angiotensin II signaling within the aging arterial wall 29930755 2018 Pintus, G;Giordo, R;Wang, Y;Zhu, W;Kim, SH;Zhang, L;Ni, L;Zhang, J;Telljohann, R;McGraw, KR;Monticone, RE;Ferris, C;Liu, L;Wang, M;Lakatta, EG; Oncotarget SLITL2 13854-H08H
Chrono-pharmacological Targeting of the CCL2-CCR2 Axis Ameliorates Atherosclerosis 29861387 2018 Winter, C;Silvestre-Roig, C;Ortega-Gomez, A;Lemnitzer, P;Poelman, H;Schumski, A;Winter, J;Drechsler, M;de Jong, R;Immler, R;Sperandio, M;Hristov, M;Zeller, T;Nicolaes, GAF;Weber, C;Viola, JR;Hidalgo, A;Scheiermann, C;Soehnlein, O; Cell Metab. VCAM1 50163-M08H
PRDM4 mediates YAP-induced cell invasion by activating leukocyte-specific integrin β2 expression 29669796 2018 Liu, H;Dai, X;Cao, X;Yan, H;Ji, X;Zhang, H;Shen, S;Si, Y;Zhang, H;Chen, J;Li, L;Zhao, JC;Yu, J;Feng, XH;Zhao, B; EMBO Rep. VCAM1 10113-H02H
Generation of a monoclonal antibody recognizing the heavily glycosylated CD45 protein and its application on identifying circulating tumor cells 29425242 2018 Zhang, W;Li, Z;Wang, Z;Yue, C;Zheng, H;Li, R;Zhou, M;Hu, Z;Wei, Z;Li, Q; PLoS ONE vector CV003
IMP/GTP balance modulates cytoophidium assembly and IMPDH activity 29946345 2018 Keppeke, GD;Chang, CC;Peng, M;Chen, LY;Lin, WC;Pai, LM;Andrade, LEC;Sung, LY;Liu, JL; Cell Div vector vector
β-Asarone Induces Apoptosis and Cell Cycle Arrest of Human Glioma U251 Cells via Suppression of HnRNP A2/B1-Mediated Pathway In Vitro and In Vivo 29751524 2018 Li, L;Yang, Y;Wu, M;Yu, Z;Wang, C;Dou, G;He, H;Wang, H;Yang, N;Qi, H;Xu, X; Molecules vector vector
Combinatorial effects of VEGFR kinase inhibitor axitinib and oncolytic virotherapy in mouse and human glioblastoma stem-like cell models 29599413 2018 Saha, D;Wakimoto, H;Peters, CW;Antoszczyk, SJ;Rabkin, SD;Martuza, RL; Clin. Cancer Res. VEGFA 50159-MNAB
Impacts of CyhospitalclinE downstream vimentin on proliferation, invasion and apoptosis of hepatoma HepG2 cell 2018 Hu, G;Jia, F;Gao, N;Han, Y; International Journal of Clinical and Experimental Medicine Vimentin 100254-T40
Bioluminescent Probe for Detection of Starvation-Induced Pantetheinase Upregulation 29976064 2018 Lin, Y;Gao, Y;Ma, Z;Li, Z;Tang, C;Qin, X;Zhang, Z;Wang, G;Du, L;Li, M; Anal. Chem. VNN1 HG11662-ACR
Dually Modified Transmembrane Proteoglycan TβRIII/Betaglycan in Cell Signaling and Cancer 2018 Jenkins, LM; Thesis Wnt5a MG50154-NF
Positive Regulation of Transcription by Human ZMYND8 through Its Association with P-TEFb Complex 30134174 2018 Ghosh, K;Tang, M;Kumari, N;Nandy, A;Basu, S;Mall, DP;Rai, K;Biswas, D; Cell Rep ZMYND8 HG16278-G
Expression of Programmed cell death protein 1 (PD-1) and Indoleamine 2,3-dioxygenase (IDO) in the tumor microenvironment and in tumor-draining lymph nodes of breast cancer 29447919 2018 Ye, Q;Wang, C;Xian, J;Zhang, M;Cao, Y;Cao, Y; Hum. Pathol. Secondary antibodies SSA004
Expression of Programmed cell death protein 1 (PD-1) and Indoleamine 2,3-dioxygenase (IDO) in the tumor microenvironment and in tumor-draining lymph nodes of breast cancer 29447919 2018 Ye, Q;Wang, C;Xian, J;Zhang, M;Cao, Y;Cao, Y; Hum. Pathol. Secondary antibodies SSA007
The Transcription Factor AP4 Promotes Oncogenic Phenotypes and Cisplatin Resistance by Regulating LAPTM4B Expression 29378908 2018 Wang, L;Meng, Y;Xu, JJ;Zhang, QY; Mol. Cancer Res. Secondary antibodies CR2
Structure of the human voltage-gated sodium channel Nav1.4 in complex with β1 30190309 2018 Pan, X;Li, Z;Zhou, Q;Shen, H;Wu, K;Huang, X;Chen, J;Zhang, J;Zhu, X;Lei, J;Xiong, W;Gong, H;Xiao, B;Yan, N; Science medium SMM 293T-I
NKILA lncRNA promotes tumor immune evasion by sensitizing T cells to activation-induced cell death 2018 Huang, D;Chen, J;Yang, L;Ouyang, Q;Li, J;Lao, L;Zhao, J;Liu, J;Lu, Y;Xing, Y;Chen, F;Su, F;Yao, H;Liu, Q;Su, S;Song, E; Nat. Immunol. NF-kB p65 12054-H09E
NKILA lncRNA promotes tumor immune evasion by sensitizing T cells to activation-induced cell death 2018 Huang, D;Chen, J;Yang, L;Ouyang, Q;Li, J;Lao, L;Zhao, J;Liu, J;Lu, Y;Xing, Y;Chen, F;Su, F;Yao, H;Liu, Q;Su, S;Song, E; Nat. Immunol. IkB alpha 12045-H07E
An OB-fold complex controls the repair pathways for DNA double-strand breaks 30254264 2018 Gao, S;Feng, S;Ning, S;Liu, J;Zhao, H;Xu, Y;Shang, J;Li, K;Li, Q;Guo, R;Xu, D; Nat Commun medium SMM 293-TI
Alpha-enolase regulates the malignant phenotype of pulmonary artery smooth muscle cells via the AMPK-Akt pathway 30242159 2018 Dai, J;Zhou, Q;Chen, J;Rexius-Hall, ML;Rehman, J;Zhou, G; Nat Commun ENO1 HG11554-ACG
Structure of the human plasma membrane Ca2+-ATPase 1 in complex with its obligatory subunit neuroplastin 30190470 2018 Gong, D;Chi, X;Ren, K;Huang, G;Zhou, G;Yan, N;Lei, J;Zhou, Q; Nat Commun medium SMM 293T-I
TRIM59 regulates autophagy through modulating both the transcription and the ubiquitination of BECN1 30231667 2018 Han, T;Guo, M;Gan, M;Yu, B;Tian, X;Wang, JB; Autophagy UBE2D1 11432-H07E
Novel antibodies against GPIbα inhibit pulmonary metastasis by affecting vWF-GPIbα interaction 30223883 2018 Qi, Y;Chen, W;Liang, X;Xu, K;Gu, X;Wu, F;Fan, X;Ren, S;Liu, J;Zhang, J;Li, R;Liu, J;Liang, X; J Hematol Oncol Von Willebrand Factor 10973-H08C
Sublytic C5b-9 Induces Glomerular Mesangial Cell Apoptosis Through miR-3546/SOX4/Survivin Axis in Rat Thy-1 Nephritis 30235450 2018 Yao, C;He, F;Liu, L;Zhang, Z;Zhao, C;Qiu, W;Zhao, D;Zhang, J;Xie, M;Gong, Y;Yu, T;Xia, L;Qian, B;Wang, Y; Cell. Physiol. Biochem. C6 12426-H08H
Reversal of Triple-negative Breast Cancer EMT by miR-200c Decreases Tryptophan Catabolism and a Program of Immune-Suppression 2018 Rogers, TJ;Christenson, JL;Greene, LI;O'Neill, KI;Williams, MM;Gordon, MA;Nemkov, T;D'Alessandro, A;DeGala, GD;Shin, J;Tan, AC;Cittelly, DM;Lambert, JR;Richer, JK; Mol. Cancer Res. TDO2 HG13215-UT
EFab domain substitution as a solution to the light-chain pairing problem of bispecific antibodies 30215570 2018 Cooke, HA;Arndt, J;Quan, C;Shapiro, RI;Wen, D;Foley, S;Vecchi, MM;Preyer, M; MAbs TNF alpha 10602-H01H
Influenza Virus NS1 Protein RNA-Interactome Reveals Intron Targeting 30258002 2018 Zhang, L;Wang, J;Muñoz-Moreno, R;Kim, M;Sakthivel, R;Mo, W;Shao, D;Anantharaman, A;García-Sastre, A;Conrad, NK;Fontoura, BMA; J. Virol. IFN-beta 10704-HNAS
The intrinsically disordered C-terminal F domain of the ecdysteroid receptor from Aedes aegypti exhibits metal ion-binding ability 30243841 2018 Więch, A;Rowińska-Żyrek, M;Wątły, J;Czarnota, A;Hołubowicz, R;Szewczuk, Z;Ożyhar, A;Orłowski, M; J. Steroid Biochem. Mol. Biol. 3c protease S3CP01
Anxa4 mediated airway progenitor cell migration promotes distal epithelial cell fate specification 30254199 2018 Jiang, K;Tang, Z;Li, J;Wang, F;Tang, N; Sci Rep FGF10 10573-HNAE
Predictions of novel Schistosoma mansoni - human protein interactions consistent with experimental data 30166569 2018 White Bear, J;Long, T;Skinner, D;McKerrow, JH; Sci Rep Elafin 12187-H08H
Towards a combinatorial approach for the prediction of immunoglobulin G half-life and clearance 2018 Goulet, DR;Watson, MJ;Tam, SH;Zwolak, A;Chiu, ML;Atkins, WM;Nath, A; Drug Metab. Dispos. FCRN/FCGRT CT009-H08H
Endoglin Mediates Vascular Endothelial Growth Factor-A-Induced Endothelial Cell Activation by Regulating Akt Signaling 30248336 2018 Bus, P;Gerrits, T;Heemskerk, SAC;Zandbergen, M;Wolterbeek, R;Bruijn, JA;Baelde, HJ;Scharpfenecker, M; Am. J. Pathol. VCAM1 HP100188
Generation of Fcabs targeting human and murine LAG-3 as building blocks for novel bispecific antibody therapeutics 30208333 2018 Everett, KL;Kraman, M;Wollerton, FPG;Zimarino, C;Kmiecik, K;Gaspar, M;Pechouckova, S;Allen, NL;Doody, JF;Tuna, M; Methods IgG2a 51094-MNAH
Schisandrin B exhibits potent anticancer activity in triple negative breast cancer by inhibiting STAT3 30195018 2018 Dai, X;Yin, C;Guo, G;Zhang, Y;Zhao, C;Qian, J;Wang, O;Zhang, X;Liang, G; Toxicol. Appl. Pharmacol. STAT3 HG10034-CF
Updated protocols for the detection of Sotatercept and Luspatercept in human serum 30203930 2018 Reichel, C;Gmeiner, G;Walpurgis, K;Thevis, M; Drug Test Anal ACVR2A 10257-T52
Updated protocols for the detection of Sotatercept and Luspatercept in human serum 30203930 2018 Reichel, C;Gmeiner, G;Walpurgis, K;Thevis, M; Drug Test Anal ACVR2B 10229-T20
Total and high-affinity corticosteroid-binding globulin depletion in septic shock is associated with mortality 30160799 2018 Meyer, EJ;Nenke, MA;Rankin, W;Lewis, JG;Konings, E;Slager, M;Jansen, TC;Bakker, J;Hofland, J;Feelders, RA;Torpy, DJ; Clin. Endocrinol. (Oxf) CBG 10998-H08H