Drug Target for Cancer: CD96

Drug Targets for Cancer: CD96 and Cancer

CD96 has been reported to be expressed in T and NK cells, but not in B cells, granulocytes, monocytes, or RBCs. In nonhematopoietic tissue, CD96 is expressed in the convoluted tubular epithelium of the kidney, the mucosal epithelium of the small and large intestines, and the vascular endothelium. It was also reported that CD96 is expressed in ≈30% of human AML samples, regardless of disease subtype, by examining whole BM cells from AML patients with immunohistochemical-staining; its expression was rare in the FAB-M5 subtype.

Drug Targets for Cancer: CD96 related Products

Other vital drug targets for cancer like CD96:

Drug Targets for Cancer: CD96 Related Reference

Hosen N, Park CY, Tatsumi N, et al. CD96 is a leukemic stem cell-specific marker in human acute myeloid leukemia. Proceedings of the National Academy of Sciences of the United States of America. 2007;104(26):11008-11013.

Drug Targets for Cancer: CD96 Related Information