| CD133 Gene ID | 8842 |
| CD133 Official Full Name | prominin 1 |
| CD133 Alias | PROM1, RP41, AC133, MCDR2, STGD4, CORD12, PROML1, MSTP061 |
| CD133 Cellular Expression | Epithelial; Endothelial |
| CD133 Ligand/Receptor/Association | |
| CD133 Function | CD133 has been proposed to act as an organizer of cell membrane topology |
| CD133 Summary | This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] |
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