CD16a Gene ID | 14131 |
CD16a Official Full Name | Fc receptor, IgG, low affinity III |
CD16a Alias | FcγRIIIA, FCGR3A, FCG3, FCGR3, IGFR3 |
CD16a Cellular Expression | T; NK; Dendritic; Granulocyte; Macrophage |
CD16a Ligand/Receptor/Association | aggregated IgG, IgG-Ag complex |
CD16a Function | Low affinity Fc receptor. Mediates phagocytosis and antibody-dependent T-cell-mediated cytotoxicity |
CD16a Summary | CD16 is a low affinity Fc receptor. It is a cluster of differentiation molecule found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages.[1] It can be used to isolate populations of these cells by antibodies directed towards CD16, using fluorescent-activated cell sorting or magnetic-activated cell sorting |
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