| CD344 Gene ID | 8322 |
| CD344 Official Full Name | frizzled class receptor 4 |
| CD344 Alias | Frizzled-4, Fz-4, FzD4 |
| CD344 Cellular Expression | Endothelial; Epithelial; Stem cell |
| CD344 Ligand/Receptor/Association | Norrin, Wnt proteins |
| CD344 Function | Receptor for Wnt proteins |
| CD344 Summary | This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq, Jul 2008] |
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